Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 3/20 | 0.39 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.39 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9630101 | 0.84 | TRPV4 (0.37) | TRPV4KDM4EALDH1A1HPGDCTSS | |
| SCHEMBL9630094 | 0.84 | TRPV4 (0.37) | TRPV4KDM4EALDH1A1HPGDCTSS | |
| SCHEMBL15043539 | 0.84 | TRPV4 (0.37) | TRPV4CTSSCTSKMAOBMAOA | |
| SCHEMBL9260065 | 0.81 | DAO (0.44) | DAOPARP14PDGFRBPDGFRAMAOB | |
| SCHEMBL9631070 | 0.81 | TRPV4 (0.34) | TRPV4MAOBMAOAHRH3 | |
| SCHEMBL9630172 | 0.81 | TRPV4 (0.34) | TRPV4MAOBMAOAHRH3 | |
| SCHEMBL9630169 | 0.81 | TRPV4 (0.34) | TRPV4MAOBMAOAHRH3 | |
| SCHEMBL9061364 | 0.81 | TRPV4 (0.34) | TRPV4MAOBMAOAHRH3 | |
| SCHEMBL9061373 | 0.81 | TRPV4 (0.34) | TRPV4MAOBMAOAHRH3 | |
| SCHEMBL9061356 | 0.81 | TRPV4 (0.34) | TRPV4MAOBMAOAHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |