SCHEMBL15043548

SCHEMBL15043548

CCCOP(=O)(O)OCC(CO)OCCCCC(=O)OC

nearest known ligand 0.45

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.45
▸ PLA2G2C Q5R387 1/20 0.43
▸ ENPP2 Q13822 4/20 0.42
▸ P2RY10 O00398 4/20 0.42
▸ GPR34 Q9UPC5 2/20 0.42
▸ LPAR1 Q92633 4/20 0.42
▸ LPAR3 Q9UBY5 4/20 0.42
▸ LPAR6 P43657 1/20 0.41
▸ LPAR4 Q99677 1/20 0.41
▸ LPAR5 Q9H1C0 1/20 0.41
▸ LPAR2 Q9HBW0 1/20 0.41
▸ PLA2G2A P14555 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15133363 0.91 FABP3 (0.46) FABP3PLA2G2CENPP2P2RY10GPR34
SCHEMBL15161266 0.89 PLA2G2C (0.46) FABP3PLA2G2CENPP2P2RY10GPR34
SCHEMBL19354801 0.87 LPAR1 (0.44) FABP3PLA2G2CP2RY10GPR34LPAR1
SCHEMBL15942985 0.87 LPAR1 (0.44) FABP3PLA2G2CP2RY10GPR34LPAR1
SCHEMBL15161242 0.87 FABP3 (0.55) FABP3P2RY10GPR34
SCHEMBL19354790 0.86 LPAR1 (0.46) FABP3PLA2G2CP2RY10GPR34LPAR1
SCHEMBL18164945 0.82 FABP3 (0.35) FABP3ENPP2P2RY10GPR34PLA2G2A
SCHEMBL8797728 0.81 TSHR (0.48) LPAR1LPAR3LPAR6LPAR4LPAR5
SCHEMBL13271118 0.80 FABP3 (0.64) FABP3ENPP2LPAR1LPAR3LPAR6
SCHEMBL12348817 0.79 PLA2G2C (0.64) FABP3PLA2G2CENPP2P2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170246197-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-08-31 — — US disclosed
US-9566288-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2017-02-14 — — US disclosed
US-20150216882-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-08-06 — — US disclosed
US-9006217-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2015-04-14 — — US disclosed
US-8802875-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2014-08-12 — — US disclosed
US-8759557-B2 Process for the preparation of oxidized phospholipids VASCULAR BIOGENICS LTD. (IL) 2014-06-24 — — US disclosed
US-8569529-B2 High-purity phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-10-29 — — US disclosed
US-20130237720-A1 High-Purity Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-09-12 — — US disclosed
US-20130158283-A1 Process for the Preparation of Oxidized Phospholipids VASCULAR BIOGENICS LTD. (IL) 2013-06-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20150216882-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 FABP3 478/4885PLA2G2C 13/4885ENPP2 50/4885
US-20130158283-A1 Process for the Preparation of Oxidized Phospholipids PHOSPHO1, SGMS1, SGMS2 FABP3 1014/4885PLA2G2C 19/4885ENPP2 106/4885
US-20170246197-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 FABP3 478/4885PLA2G2C 13/4885ENPP2 50/4885
US-20130237720-A1 High-Purity Phospholipids PHOSPHO1, SGMS1, SGMS2 FABP3 478/4885PLA2G2C 13/4885ENPP2 50/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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