SCHEMBL18164945

SCHEMBL18164945

COC(=O)CCCCOC(CO)COP(=O)(O)OCC[n+]1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
▸ FABP3 P05413 1/20 0.35
▸ P2RY10 O00398 4/20 0.35
▸ GPR34 Q9UPC5 2/20 0.35
▸ S1PR1 P21453 1/20 0.34
▸ SELP P16109 1/20 0.34
▸ PLA2G2A P14555 2/20 0.32
▸ ENPP2 Q13822 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18164944 0.89 LPAR1 (0.32) FABP3P2RY10GPR34SELP
SCHEMBL18164946 0.88 LPAR1 (0.36) FABP3P2RY10GPR34PLA2G2A
SCHEMBL18161730 0.87 LPAR1 (0.50) FABP3P2RY10GPR34
SCHEMBL18161723 0.87 LPAR1 (0.50) FABP3P2RY10GPR34
SCHEMBL18161721 0.83 LPAR1 (0.41) FABP3P2RY10GPR34PLA2G2AENPP2
SCHEMBL15043548 0.82 FABP3 (0.45) FABP3P2RY10GPR34PLA2G2AENPP2
SCHEMBL15161266 0.81 PLA2G2C (0.46) FABP3P2RY10GPR34PLA2G2AENPP2
SCHEMBL15161242 0.79 FABP3 (0.55) FABP3P2RY10GPR34
SCHEMBL18164942 0.78 LPAR1 (0.38) FABP3P2RY10GPR34
SCHEMBL18161727 0.78 LPAR1 (0.53) FABP3P2RY10GPR34

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9771385-B2 Oxidized lipids VASCULAR BIOGENICS LTD. (IL) 2017-09-26 — — US disclosed
US-20160304544-A1 Oxidized Lipids and Methods of Use Thereof VASCULAR BIOGENICS LTD. (IL) 2016-10-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160304544-A1 Oxidized Lipids and Methods of Use Thereof LPO, LIPA, GPX4 FABP3 335/4885P2RY10 2636/4885GPR34 3025/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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