Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.51 |
| ▸ | QDPR | P09417 | 4/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | ACMSD | Q8TDX5 | 2/20 | 0.34 |
| ▸ | AR | P10275 | 3/20 | 0.34 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CSF1R | P07333 | 2/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14660515 | 0.92 | QDPR (0.46) | ESR2QDPRUSP30ACMSDAR | |
| SCHEMBL31335 | 0.83 | USP30 (0.46) | ESR2USP30ARHCRTR2MEN1 | |
| SCHEMBL14601387 | 0.81 | CYP2C9 (0.48) | ESR2QDPRUSP30ARMEN1 | |
| SCHEMBL31343 | 0.81 | KDM1A (0.43) | ESR2KDM1A | |
| SCHEMBL14274413 | 0.81 | KDM1A (0.43) | ESR2KDM1A | |
| SCHEMBL1850160 | 0.78 | QDPR (0.46) | ESR2QDPRACMSDARKDM1A | |
| SCHEMBL14228793 | 0.77 | KDM1A (0.41) | ESR2KDM1A | |
| SCHEMBL15112858 | 0.75 | USP30 (0.47) | ESR2USP30ARHCRTR2 | |
| SCHEMBL26391946 | 0.74 | ESR2 (0.44) | ESR2USP30ARHCRTR2 | |
| SCHEMBL8972921 | 0.74 | KDM1A (0.40) | ESR2KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-9617473-B2 | Switch element comprising a liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2017-04-11 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |