Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM1A | O60341 | 6/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.43 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 6/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 6/20 | 0.38 |
| ▸ | FASN | P49327 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.36 |
| ▸ | TRPC3 | Q13507 | 1/20 | 0.35 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14274413 | 1.00 | KDM1A (0.43) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL14228793 | 0.95 | KDM1A (0.41) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL11963260 | 0.92 | TRPV4 (0.50) | KDM1ATRPV4CHEK1CYP11B1CYP11B2 | |
| SCHEMBL8972905 | 0.92 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL8972914 | 0.92 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL8972902 | 0.92 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL8972921 | 0.92 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL8972910 | 0.92 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1CYP11B1 | |
| SCHEMBL14649655 | 0.88 | CYP11B1 (0.47) | KDM1AESR2CYP11B1CYP11B2 | |
| SCHEMBL6451880 | 0.86 | KDM1A (0.40) | KDM1AESR2TRPV4CHEK1CYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3802730-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-04-19 | — | — | EP | disclosed |
| EP-3529333-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| EP-3529332-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2020-11-25 | — | — | EP | disclosed |
| WO-2019233913-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-12-12 | — | — | WO | disclosed |
| WO-2019154740-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-15 | — | — | WO | disclosed |
| EP-3368637-B1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-08-07 | — | — | EP | disclosed |
| WO-2019110473-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-06-13 | — | — | WO | disclosed |
| WO-2019025398-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2019-02-07 | — | — | WO | disclosed |
| WO-2018073158-A1 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-04-26 | — | — | WO | disclosed |
| WO-2018073159-A2 | LIQUID-CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2018-04-26 | — | — | WO | disclosed |
| US-20130208227-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-08-15 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| US-8202447-B2 | Method for producing liquid crystal composition | DIC CORPORATION (JP) | 2012-06-19 | — | — | US | disclosed |
| WO-2012052100-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| US-20100012896-A1 | METHOD FOR PRODUCING LIQUID CRYSTAL COMPOSITION | DIC CORPORATION (JP) | 2010-01-21 | — | — | US | disclosed |
| US-7335404-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-26 | — | — | US | disclosed |
| US-7335404-B2 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-26 | — | — | US | disclosed |
| US-20070080325-A1 | Liquid crystal composition for use in bistable liquid crystal devices | MERCK PATENT GMBH (DE) | 2007-04-12 | — | — | US | disclosed |