SCHEMBL15043679

SCHEMBL15043679

CCCCC1(c2ccc(Cl)cc2)CCCCC1

nearest known ligand 0.59

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A4 P31645 15/20 0.59
SLC6A3 Q01959 15/20 0.59
SLC6A2 P23975 7/20 0.58
CNR2 P34972 4/20 0.46
CNR1 P21554 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2422 0.90 SLC6A4 (0.54) SLC6A4SLC6A3SLC6A2CNR2CNR1
SCHEMBL12002388 0.89 SLC6A4 (0.62) SLC6A4SLC6A3SLC6A2
SCHEMBL15043618 0.87 SLC6A4 (0.59) SLC6A4SLC6A3SLC6A2
SCHEMBL9399121 0.85 CNR2 (0.57) SLC6A4SLC6A3SLC6A2CNR2CNR1
SCHEMBL15043625 0.84 SLC6A4 (0.55) SLC6A4SLC6A3SLC6A2
SCHEMBL12002389 0.83 SLC6A3 (0.59) SLC6A4SLC6A3SLC6A2CNR2CNR1
SCHEMBL28168403 0.83 CNR2 (0.46) SLC6A4SLC6A3SLC6A2CNR2CNR1
SCHEMBL5682331 0.83 CNR2 (0.52) SLC6A4SLC6A3SLC6A2CNR2CNR1
SCHEMBL15568275 0.82 SLC6A4 (0.56) SLC6A4SLC6A3SLC6A2CNR2CNR1
SCHEMBL15042375 0.82 SLC6A4 (0.54) SLC6A4SLC6A3SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8822510-B2 Substituted 3-phenyl-1,2,4-Oxadiazole compounds BRISTOL-MYERS SQUIBB COMPANY (US) 2014-09-02 US disclosed
US-20130158001-A1 SUBSTITUTED 3-PHENYL-1,2,4-OXADIAZOLE COMPOUNDS BRISTOL-MYERS SQUBIB COMPANY 2013-06-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130158001-A1 SUBSTITUTED 3-PHENYL-1,2,4-OXADIAZOLE COMPOUNDS S1PR1, S1PR3, S1PR2 SLC6A4 2698/4885SLC6A3 2766/4885SLC6A2 2889/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.