Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 2/20 | 0.32 |
| ▸ | TRIM33 | Q9UPN9 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15044262 | 0.86 | — | — | |
| SCHEMBL15062057 | 0.81 | — | — | |
| SCHEMBL10638515 | 0.66 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642871 | 0.64 | TRIM24 (0.50) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL18642898 | 0.61 | TRIM24 (0.47) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL6250876 | 0.61 | TRIM24 (0.35) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL4309011 | 0.59 | TRIM24 (0.39) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL40325 | 0.59 | TRIM24 (0.39) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL15062064 | 0.58 | TRIM24 (0.32) | TRIM24TRIM33ALDH1A1 | |
| SCHEMBL6666733 | 0.57 | TRIM24 (0.42) | TRIM24TRIM33ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3707132-B1 | NEW METHOD FOR THE SYNTHESIS OF UNSYMMETRICAL TERTIARY AMINES | UNIV PARIS SACLAY (FR) | 2024-07-17 | — | — | EP | disclosed |
| US-8513410-B2 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | LES LABORATOIRES SERVIER (FR) | 2013-08-20 | — | — | US | disclosed |
| US-8513410-B2 | Process for the synthesis of ivabradine and addition salts thereof with a pharmaceutically acceptable acid | LES LABORATOIRES SERVIER (FR) | 2013-08-20 | — | — | US | disclosed |
| EP-2607353-A1 | New method for synthesising ivabradine and its added salts with a pharmaceutically acceptable acid. | Les Laboratoires Servier (FR) | 2013-06-26 | — | — | EP | disclosed |
| US-20130158256-A1 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABORATOIRES SERVIER (FR) | 2013-06-20 | — | — | US | disclosed |
| US-20130158256-A1 | PROCESS FOR THE SYNTHESIS OF IVABRADINE AND ADDITION SALTS THEREOF WITH A PHARMACEUTICALLY ACCEPTABLE ACID | LES LABORATOIRES SERVIER (FR) | 2013-06-20 | — | — | US | disclosed |