Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.43 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.42 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055708 | 0.86 | CYP2C9 (0.55) | HTTLMNARAB9AALDH1A1HPGD | |
| SCHEMBL15044160 | 0.86 | HPGD (0.51) | HTTLMNARAB9AALDH1A1HPGD | |
| SCHEMBL10055308 | 0.86 | SMN1; SMN2 (0.49) | HTTLMNARAB9AALDH1A1HPGD | |
| SCHEMBL15044457 | 0.82 | HPGD (0.50) | HTTLMNARAB9AALDH1A1HPGD | |
| SCHEMBL10055513 | 0.80 | CYP2C9 (0.51) | HTTALDH1A1HPGDPOLBKMT2A | |
| SCHEMBL10057425 | 0.77 | CYP2C9 (0.59) | RAB9AALDH1A1HPGDNPC1KMT2A | |
| SCHEMBL10057406 | 0.75 | CYP2C9 (0.57) | HTTLMNARAB9AALDH1A1HPGD | |
| SCHEMBL15044032 | 0.74 | SMN1; SMN2 (0.42) | HTTLMNAALDH1A1HPGDNPC1 | |
| SCHEMBL10056291 | 0.74 | TSHR (0.56) | HTTLMNAHPGDPOLBKMT2A | |
| SCHEMBL27892112 | 0.73 | HTT (1.00) | HTTLMNARAB9AALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013089212-A1 | SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME | 塩野義製薬株式会社 (JP) | 2013-06-20 | — | — | WO | disclosed |