SCHEMBL15044032 — predicted protein targets

Predicted protein targets (top 11)

	gene	UniProt	supporting neighbours	confidence
▸	SMN1; SMN2	Q16637	3/20	0.42

▸	NPC1	O15118	1/20	0.41

▸	ALDH1A1	P00352	4/20	0.41

▸	PKM	P14618	2/20	0.40

▸	MAPK14	Q16539	1/20	0.40

▸	KMT2A	Q03164	4/20	0.40

▸	KDM4E	B2RXH2	2/20	0.40

▸	HPGD	P15428	2/20	0.40

▸	MEN1	O00255	2/20	0.40

▸	HTT	P42858	1/20	0.40

▸	LMNA	P02545	2/20	0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL10055235	0.90	PPID (0.45)	SMN1; SMN2NPC1ALDH1A1KMT2AMEN1
SCHEMBL10055429	0.88	CYP2C9 (0.50)	SMN1; SMN2NPC1ALDH1A1KMT2AHPGD
SCHEMBL10055308	0.88	SMN1; SMN2 (0.49)	SMN1; SMN2NPC1ALDH1A1MAPK14KMT2A
SCHEMBL10056343	0.83	PPID (0.43)	SMN1; SMN2NPC1HPGDLMNA
SCHEMBL10056203	0.80	SMN1; SMN2 (0.49)	SMN1; SMN2NPC1ALDH1A1KMT2AKDM4E
SCHEMBL10055187	0.77	L3MBTL1 (0.44)	SMN1; SMN2NPC1ALDH1A1PKMMAPK14
SCHEMBL10055475	0.75	ATM (0.42)	SMN1; SMN2NPC1ALDH1A1PKMMAPK14
SCHEMBL10056409	0.74	ALDH1A1 (0.44)	SMN1; SMN2NPC1ALDH1A1PKMMAPK14
SCHEMBL10055708	0.74	CYP2C9 (0.55)	SMN1; SMN2NPC1ALDH1A1KMT2AHPGD
SCHEMBL10057425	0.74	CYP2C9 (0.59)	SMN1; SMN2NPC1ALDH1A1KMT2AHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2013089212-A1	SUBSTITUTED TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SAME	塩野義製薬株式会社 (JP)	2013-06-20	—	—	WO	disclosed