Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.42 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10055187 | 0.89 | L3MBTL1 (0.44) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL10055797 | 0.88 | CARM1 (0.47) | TSHRMEN1KMT2AHPGDCA12 | |
| SCHEMBL10055319 | 0.88 | CYP2C9 (0.48) | TSHRMEN1KMT2ACARM1PRMT6 | |
| SCHEMBL10056387 | 0.81 | CARM1 (0.47) | GAAMEN1KMT2ACARM1PRMT6 | |
| SCHEMBL15044457 | 0.79 | HPGD (0.50) | TSHRKMT2AHPGDHTTL3MBTL1 | |
| SCHEMBL10055215 | 0.79 | SMN1; SMN2 (0.46) | GAAMEN1KMT2AHPGDHTT | |
| SCHEMBL10055489 | 0.78 | CYP2C9 (0.50) | TSHRGAAMEN1KMT2AHPGD | |
| SCHEMBL15044160 | 0.77 | HPGD (0.51) | TSHRKMT2AHPGDHTTL3MBTL1 | |
| SCHEMBL10055475 | 0.75 | ATM (0.42) | TSHRMEN1KMT2AHPGDCA7 | |
| SCHEMBL15044540 | 0.74 | HTT (0.57) | KMT2AHPGDHTTCA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012020749-A1 | TRIAZINE DERIVATIVE AND PHARMACEUTICAL COMPOUND THAT CONTAINS SAME AND EXHIBITS ANALGESIC ACTIVITY | 塩野義製薬株式会社 (JP) | 2012-02-16 | — | — | WO | disclosed |