Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.63 |
| ▸ | MME | P08473 | 4/20 | 0.52 |
| ▸ | CPA1 | P15085 | 1/20 | 0.52 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.52 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | NPY4R | P50391 | 5/20 | 0.50 |
| ▸ | NPY1R | P25929 | 3/20 | 0.50 |
| ▸ | NPY2R | P49146 | 3/20 | 0.50 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.50 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.50 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.50 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.50 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MMP1 | P03956 | 1/20 | 0.48 |
| ▸ | FCER2 | P06734 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15328423 | 0.89 | ACE (0.62) | ACEMMECPA1ACE2PTPN2 | |
| SCHEMBL15328426 | 0.89 | ACE (0.62) | ACEMMECPA1ACE2PTPN2 | |
| SCHEMBL14520481 | 0.89 | ACE (0.53) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL9555596 | 0.87 | ACE (0.59) | ACEMMECPA1ACE2PTPN2 | |
| SCHEMBL9555600 | 0.87 | ACE (0.59) | ACEMMECPA1ACE2PTPN2 | |
| SCHEMBL24558040 | 0.86 | ACE (0.51) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL14269021 | 0.86 | FCER2 (0.62) | ACEMMECPA1ACE2ERAP2 | |
| SCHEMBL15851264 | 0.86 | FCER2 (0.62) | ACEMMECPA1ACE2ERAP2 | |
| SCHEMBL6465852 | 0.86 | MME (0.68) | ACEMMECPA1ACE2FOLH1 | |
| SCHEMBL25827830 | 0.86 | ACE (0.53) | ACEMMECPA1ACE2FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9289510-B2 | Polymeric drug delivery conjugates and methods of making and using thereof | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2016-03-22 | — | — | US | disclosed |
| US-20130156722-A1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130156722-A1 | POLYMERIC DRUG DELIVERY CONJUGATES AND METHODS OF MAKING AND USING THEREOF | CD44, MMP7, MMP26 | ACE 1948/4885MME 475/4885CPA1 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.