MMP26 — patent landscape

Top predicted compounds (top 20 by supporting neighbours, then confidence)

Compound	Confidence	Supporting neighbours
SCHEMBL3534852	0.77	11/20
SCHEMBL3534006	0.66	11/20
SCHEMBL5164250	0.69	10/20
SCHEMBL3534115	0.67	10/20
SCHEMBL3536039	0.67	10/20
SCHEMBL3537910	0.63	10/20
SCHEMBL1021988	0.63	10/20
SCHEMBL5439966	0.60	10/20
SCHEMBL5439969	0.60	10/20
SCHEMBL1022551	0.58	10/20
SCHEMBL1022069	0.57	10/20
SCHEMBL1023240	0.56	10/20
SCHEMBL4692975	0.56	10/20
SCHEMBL5445428	0.56	10/20
SCHEMBL5451005	0.56	10/20
SCHEMBL1022410	0.54	10/20
SCHEMBL5431767	0.51	10/20
SCHEMBL5431771	0.51	10/20
SCHEMBL5449195	0.51	10/20
SCHEMBL1020024	0.66	9/20

Clinical trials — most relevant to MMP26 by text similarity (a relevance ranking, not an exhaustive list)

Trial	Phase	Status
Doxycycline In Lymphangioleiomyomatosis (LAM)	PHASE4	COMPLETED
Estimation of MMP-8 Levels in GCF and Serum and Its Correlation With Wound Healing and Clinical Outcomes After Coronally Advanced Flap and Subepithelial Connective Tissue Graft for Root Coverage in Recession Defects: A CLINICO-BIOCHEMICAL STUDY	PHASE4	SUSPENDED
Sputum Matrix Metalloproteinases (MMP) mRNA and Montelukast	PHASE2	COMPLETED
A Study of Sorafenib in Patients With Chemonaive Metastatic Uveal Melanoma	PHASE2	UNKNOWN
A Phase I Study of Oral COL-3 (NSC-683551), a Matrix Metalloproteinase Inhibitor, in Patients With Refractory Metastatic Cancer	PHASE1	COMPLETED
The Role of Matrix Metalloproteinases (MMPs) in Orthodontic Tooth Movement	PHASE1	COMPLETED
Influence of Statins in Artery Aneurysms	nan	UNKNOWN
Evaluation of Different Serum Cartilage Biomarkers in the Acute Response to Walking and Cycling in Healthy Male Subjects	nan	AVAILABLE
Role of A Disintegrin and Metalloproteinase (ADAM) in Epithelial Dysfunction	nan	COMPLETED
Matrix Metalloproteinase (MMP) in Heart Failure	nan	COMPLETED
Association Between Matrix Metalloproteinase-2 Gene Polymorphism rs243865 and Susceptibility to Cataract Development	nan	COMPLETED
Re-evaluation of Some Old Rheumatoid Arthritis Therapy: A Randomized Controlled Trial	nan	COMPLETED
Evaluation of Dentinal Fluid for the Presence of Matrix Metalloproteinase 9 (MMP-9) in Pulpal Inflammation	nan	COMPLETED
Correlation Between Serum Markers of Unstable Plaque and Virtual Histology of Unstable Plaque Visualized by IVUS	nan	COMPLETED
Apoptotic Changes in Gingiva Caused by Smoking	nan	COMPLETED
Case-control Study on Matrix Metalloproteinase Levels in Tissue in Patients With Keloid Scar	nan	COMPLETED
Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma	nan	UNKNOWN
Initial Management of MRONJ Stages I and II, a Clinical Trial With Detection of Salivary Biomarkers	nan	UNKNOWN
Periodontal Health in Post COVID-19 Patients	nan	UNKNOWN
Influence of Short AV Delay Permanent Pacing on Matrix Metalloproteinase Levels	nan	COMPLETED
The Effect of Non-surgical Periodontal Therapy Plus Doxycycline on HbA1c in Patients With Type 2 Diabetes Mellitus	nan	COMPLETED
Matrix Metalloproteinases After Surgery and/or Radiofrequency Ablation in Patients With Liver Metastases From Colorectal Cancer	nan	COMPLETED
Association Between Matrix Metalloproteinase-9 Gene Polymorphism and Susceptibility to Primary Open Angle Glaucoma Patients in Sohag University Hospital	nan	NOT_YET_RECRUITING
Plasma and Scarring of Diabetic Ulcers	nan	COMPLETED
Matrix Metalloproteinases and Human Papillomavirus in Dysplasias and Cancers of the Cervix	nan	COMPLETED
Salivary Markers in Periodontal Disorders	nan	COMPLETED
Detection of Cancer-Specific Active Proteases in Blood Via Fluorescence	nan	WITHDRAWN
Plasma Levels of Matrix Metalloproteinases (MMPs) and Degree of DNA Fragmentation in Pseudoexfoliation (PEX) Glaucoma	nan	COMPLETED
Influence of Exercise Program on Serum Matrix Metalloproteinases and Functional Status in Women With Postmenopausal Osteoporosis	nan	COMPLETED
Prognostic Indices of Atheromatosis Severity and Coronary Artery Bypass Surgery Outcomes for Patients With Coronary Artery Disease	nan	ACTIVE_NOT_RECRUITING

Related proteins — ESM-2 sequence neighbours (a MMP26 binder may also engage these)

Protein	Name	Similarity
Q9WTR0	—	0.985	Q9WTR0 →
Q95220	—	0.984	Q95220 →
Q5RB02	—	0.984	Q5RB02 →
Q10738	—	0.984	Q10738 →
P41245	—	0.984	P41245 →
P57748	—	0.983	P57748 →
Q11005	—	0.983	Q11005 →
MMP7	Matrilysin	0.983	landscape →
Q10739	—	0.982	Q10739 →
P53690	—	0.982	P53690 →
MMP24	Matrix metalloproteinase-24	0.981	landscape →
Q9GKE1	—	0.981	Q9GKE1 →
Q9GLE4	—	0.981	Q9GLE4 →
MMP16	Matrix metalloproteinase-16	0.981	landscape →
P50280	—	0.981	P50280 →
P97821	—	0.981	P97821 →
CTSC	Dipeptidyl peptidase 1	0.981	landscape →
O35548	—	0.981	O35548 →
P34960	—	0.980	P34960 →
MMP14	Matrix metalloproteinase-14	0.980	landscape →
B4F6N6	—	0.980	B4F6N6 →
Q5RES1	—	0.979	Q5RES1 →
MMP20	Matrix metalloproteinase-20	0.979	landscape →
P91828	—	0.979	P91828 →
G5EGM1	—	0.979	G5EGM1 →
O54732	—	0.979	O54732 →
P50282	—	0.979	P50282 →
Q63341	—	0.978	Q63341 →
P34822	—	0.978	P34822 →
O55123	—	0.978	O55123 →