Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHLPP2 | Q6ZVD8 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | THRB | P10828 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RECQL | P46063 | 3/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.46 |
| ▸ | BRCA1 | P38398 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.46 |
| ▸ | MPL | P40238 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16170914 | 0.95 | PHLPP2 (0.46) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12028012 | 0.85 | ENPP2 (0.50) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL16170719 | 0.82 | PHLPP2 (0.42) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL12028004 | 0.81 | ENPP2 (0.54) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL16170792 | 0.78 | SENP2 (0.56) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL16170803 | 0.78 | PHLPP2 (0.52) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL16170798 | 0.77 | SENP2 (0.48) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL16170716 | 0.77 | PHLPP2 (0.51) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL15044707 | 0.77 | PTPN1 (0.41) | PHLPP2KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL22413438 | 0.76 | PHLPP2 (0.50) | PHLPP2KMT2AALDH1A1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961621-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140304926-A1 | Azo Dyes | HUNTSMAN INTERNATIONAL LLC | 2014-10-16 | — | — | US | disclosed |
| WO-2013087400-A2 | AZO DYES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2013-06-20 | — | — | WO | disclosed |