Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | MPL | P40238 | 2/20 | 0.41 |
| ▸ | PHLPP2 | Q6ZVD8 | 3/20 | 0.41 |
| ▸ | SENP2 | Q9HC62 | 5/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 5/20 | 0.40 |
| ▸ | SUMO2 | P61956 | 4/20 | 0.40 |
| ▸ | SUMO1 | P63165 | 4/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 4/20 | 0.40 |
| ▸ | SENP3 | Q9H4L4 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15044924 | 1.00 | ENPP2 (0.42) | ENPP2MPLPHLPP2SENP2SENP1 | |
| SCHEMBL16170809 | 0.89 | MPL (0.53) | ENPP2MPLPHLPP2SENP2SENP1 | |
| SCHEMBL15044776 | 0.86 | SENP2 (0.48) | ENPP2PHLPP2SENP2SENP1SUMO2 | |
| SCHEMBL15044775 | 0.86 | SENP2 (0.48) | ENPP2PHLPP2SENP2SENP1SUMO2 | |
| SCHEMBL16170948 | 0.84 | SENP2 (0.41) | ENPP2MPLPHLPP2SENP2SENP1 | |
| SCHEMBL16170723 | 0.83 | SENP2 (0.59) | ENPP2PHLPP2SENP2SENP1SUMO2 | |
| SCHEMBL15044936 | 0.82 | MAPT (0.44) | ENPP2MPLPHLPP2SENP2SENP1 | |
| SCHEMBL15044934 | 0.82 | MAPT (0.44) | ENPP2MPLPHLPP2SENP2SENP1 | |
| SCHEMBL15044927 | 0.81 | PTPN11 (0.47) | ENPP2MPLPHLPP2SENP2SENP1 | |
| SCHEMBL15044911 | 0.81 | PTPN11 (0.47) | ENPP2MPLPHLPP2SENP2SENP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8961621-B2 | Azo dyes | HUNTSMAN INTERNATIONAL LLC (US) | 2015-02-24 | — | — | US | disclosed |
| US-20140304926-A1 | Azo Dyes | HUNTSMAN INTERNATIONAL LLC | 2014-10-16 | — | — | US | disclosed |
| WO-2013087400-A2 | AZO DYES | HUNTSMAN ADVANCED MATERIALS (SWITZERLAND) GMBH (CH) | 2013-06-20 | — | — | WO | disclosed |