Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 12/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 3/20 | 0.36 |
| ▸ | FAP | Q12884 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690808 | 0.83 | MEN1 (0.40) | SMYD3MEN1ALDH1A1KMT2AROCK2 | |
| SCHEMBL8379153 | 0.80 | ROCK2 (0.35) | SMYD3ROCK2DPP4HRH2HRH1 | |
| SCHEMBL8690144 | 0.80 | ROCK2 (0.35) | SMYD3ROCK2DPP4HRH2HRH1 | |
| SCHEMBL15045201 | 0.80 | DPP4 (0.49) | SMYD3MEN1ALDH1A1KMT2AROCK2 | |
| SCHEMBL14655977 | 0.73 | DPP4 (0.43) | SMYD3DPP4DPP7FAPPREP | |
| SCHEMBL15045183 | 0.73 | DPP4 (0.43) | SMYD3DPP4DPP7FAPPREP | |
| SCHEMBL30364025 | 0.73 | SMYD3 (0.52) | SMYD3MEN1ALDH1A1KMT2ADPP4 | |
| SCHEMBL22629569 | 0.73 | ALDH1A1 (0.66) | SMYD3MEN1ALDH1A1KMT2ADPP4 | |
| SCHEMBL15045202 | 0.73 | GPR119 (0.40) | SMYD3MEN1ALDH1A1KMT2AROCK2 | |
| SCHEMBL6435636 | 0.73 | ITGB3 (0.55) | SMYD3DPP4HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5747522-A | ANTICOAGULANTS; ANTIINFLAMMATORY AGENTS; ANTITUMOR AGENTS | HOFFMAN-LA ROCHE INC. (US) | 1998-05-05 | — | — | US | disclosed |
| US-5670515-A | TREATMENT OF THROMBOSIS, STROKE, CARDIAC INFARCT, INFLAMMATION, AND ARTERIOSCLEROSIS; ANTITUMOR AGENTS, WOUND HEALING AGENTS | HOFFMANN-LA ROCHE INC. (US) | 1997-09-23 | — | — | US | disclosed |