Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 4/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.36 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19702056 | 0.86 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1HTTGPR119MAPT | |
| SCHEMBL12156462 | 0.78 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1HTTMAPTEPHX2 | |
| SCHEMBL13397341 | 0.75 | ALDH1A1 (0.45) | ALDH1A1L3MBTL1MAPTPIK3CDEPHX2 | |
| SCHEMBL15029870 | 0.74 | SLC6A4 (0.38) | EPHX1 | |
| SCHEMBL2606450 | 0.73 | ALDH1A1 (0.51) | ALDH1A1L3MBTL1HTTGPR119MAPT | |
| SCHEMBL13397356 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HTTMAPTPIK3CDEPHX2 | |
| SCHEMBL19419455 | 0.72 | NPY5R (0.43) | ALDH1A1DPP4MAPTPIK3CDDPP8 | |
| SCHEMBL13658802 | 0.72 | ALDH1A1 (0.41) | ALDH1A1L3MBTL1HTTGPR119MAPT | |
| SCHEMBL19710887 | 0.72 | ALDH1A1 (0.44) | ALDH1A1L3MBTL1HTTMAPTEPHX2 | |
| SCHEMBL13662566 | 0.72 | ALDH1A1 (0.47) | ALDH1A1L3MBTL1HTTMAPTEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2604601-A1 | HETERO RING COMPOUND | Astellas Pharma Inc. (JP) | 2013-06-19 | — | — | EP | disclosed |