Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CDC25A | P30304 | 4/20 | 0.43 |
| ▸ | CDC25B | P30305 | 2/20 | 0.43 |
| ▸ | UGT2B7 | P16662 | 4/20 | 0.41 |
| ▸ | ATP1A1 | P05023 | 2/20 | 0.40 |
| ▸ | ATP1B1 | P05026 | 2/20 | 0.40 |
| ▸ | ATP1A3 | P13637 | 2/20 | 0.40 |
| ▸ | ATP1B2 | P14415 | 2/20 | 0.40 |
| ▸ | ATP1A2 | P50993 | 2/20 | 0.40 |
| ▸ | ATP1B3 | P54709 | 2/20 | 0.40 |
| ▸ | FXYD2 | P54710 | 2/20 | 0.40 |
| ▸ | ATP1A4 | Q13733 | 2/20 | 0.40 |
| ▸ | CYP17A1 | P05093 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4166573 | 0.82 | CDC25A (0.61) | GPBAR1LMNACDC25ACDC25BUGT2B7 | |
| SCHEMBL10041408 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL12247380 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL9010559 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL9010577 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL13759529 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL12190424 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL9010666 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL13325622 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B | |
| SCHEMBL13759528 | 0.81 | CDC25A (0.50) | GPBAR1LMNACDC25ACDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9775903-B2 | 1-deoxy analogs of 1,25-dihydroxyvitamin D3 compounds | JOHNS HOPKINS UNIVERSITY (US) | 2017-10-03 | — | — | US | disclosed |
| US-20130157987-A1 | 1-DEOXY ANALOGS OF 1,25-DIHYDROXYVITAMIN D3 COMPOUNDS | JOHNS HOPKINS UNIVERSITY (US) | 2013-06-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130157987-A1 | 1-DEOXY ANALOGS OF 1,25-DIHYDROXYVITAMIN D3 COMPOUNDS | CYP24A1, CYP2R1, CYP27B1 | GPBAR1 1146/4885LMNA 2415/4885CDC25A 231/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.