Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGR | P06401 | 4/20 | 0.37 |
| ▸ | PDK2 | Q15119 | 12/20 | 0.35 |
| ▸ | CHEK1 | O14757 | 3/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | GSK3A | P49840 | 1/20 | 0.31 |
| ▸ | GSK3B | P49841 | 1/20 | 0.31 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.31 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15046241 | 0.80 | PDK2 (0.36) | PGRPDK2PDK4ROCK2GSK3B | |
| SCHEMBL15046364 | 0.79 | PDK2 (0.37) | PGRPDK2CHEK1PDK4ROCK2 | |
| SCHEMBL15046376 | 0.78 | PDK2 (0.34) | PDK2PDK4 | |
| SCHEMBL12109291 | 0.76 | PDK2 (0.50) | PGRPDK2PDK4CDK5 | |
| SCHEMBL12109367 | 0.76 | PDK2 (0.50) | PGRPDK2PDK4CDK5 | |
| SCHEMBL15046238 | 0.76 | PDK2 (0.33) | PGRPDK2 | |
| SCHEMBL12776583 | 0.75 | PDK2 (0.46) | PGRPDK2PDK4 | |
| SCHEMBL12109350 | 0.72 | PDK2 (0.52) | PGRPDK2PDK4 | |
| SCHEMBL15046445 | 0.71 | PGR (0.30) | PGRPDK2 | |
| SCHEMBL16629748 | 0.70 | PGR (0.49) | PGRPDK2PDK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013089460-A1 | NOVEL CHEMICAL COMPOUND HAVING AN ACRIDINE STRUCTURE, AND ORGANIC LIGHT-EMITTING DIODE USING SAME | 주식회사 두산 (KR) | 2013-06-20 | — | — | WO | disclosed |