Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
| ▸ | CASP7 | P55210 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1504675 | 0.81 | PREP (0.37) | MEN1KMT2APOLBMAPK1CASP1 | |
| SCHEMBL10276757 | 0.78 | ADAM17 (0.38) | ADAM17 | |
| SCHEMBL995255 | 0.69 | ADAM17 (0.43) | MEN1KMT2AADAM17 | |
| SCHEMBL995012 | 0.69 | ADAM17 (0.43) | MEN1KMT2AADAM17 | |
| SCHEMBL995014 | 0.69 | ADAM17 (0.43) | MEN1KMT2AADAM17 | |
| SCHEMBL12077753 | 0.69 | TP53 (0.33) | MEN1KMT2APOLBADAM17TP53 | |
| SCHEMBL1504588 | 0.69 | ALDH1A1 (0.41) | MEN1KMT2APOLBMAPK1CASP1 | |
| SCHEMBL24269352 | 0.68 | CYP2D6 (0.44) | TDP1 | |
| Hydrochloric Acid SCHEMBL1504593 | 0.68 | ALDH1A1 (0.40) | MEN1KMT2APOLBMAPK1CASP1 | |
| Hydrochloric Acid SCHEMBL1504752 | 0.68 | ALDH1A1 (0.40) | MEN1KMT2APOLBMAPK1CASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033009-A1 | N- [2-HYDROXYCARBAMOYL-2- (PIPERAZINYL) ETHYL] BENZAMIDE COMPOUNDS, THEIR PREPARATION AND THEIR USE AS TACE INHIBITORS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2011-03-24 | — | — | WO | disclosed |