SCHEMBL15046802

SCHEMBL15046802

O=C1CCCCC(NC(=O)OCc2ccccc2)C1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 3/20 0.67
ALDH1A1 P00352 2/20 0.59
GAA P10253 1/20 0.59
CYP3A4 P08684 1/20 0.58
CYP2C9 P11712 1/20 0.58
CYP2C19 P33261 1/20 0.58
CA1 P00915 2/20 0.57
CA2 P00918 2/20 0.57
ACHE P22303 2/20 0.57
TSHR P16473 1/20 0.56
MEN1 O00255 1/20 0.55
KMT2A Q03164 1/20 0.55
CTSL P07711 1/20 0.54
CTSB P07858 1/20 0.54
CTSK P43235 1/20 0.54
TLR4 O00206 1/20 0.53
DPP4 P27487 1/20 0.49
KCNH2 Q12809 1/20 0.49
DPP7 Q9UHL4 1/20 0.49
NAAA Q02083 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19345762 0.99 EPHX1 (0.69) EPHX1ALDH1A1GAACYP3A4CYP2C9
SCHEMBL2207513 0.96 CYP3A4 (0.63) EPHX1ALDH1A1GAACYP3A4CYP2C9
SCHEMBL23898987 0.96 CYP3A4 (0.63) EPHX1ALDH1A1GAACYP3A4CYP2C9
SCHEMBL758357 0.91 ALDH1A1 (0.63) EPHX1ALDH1A1GAACYP3A4CYP2C9
SCHEMBL29248505 0.91 ALDH1A1 (0.63) EPHX1ALDH1A1GAACYP3A4CYP2C9
SCHEMBL7198149 0.86 EPHX1 (0.81) EPHX1ALDH1A1GAATSHRMEN1
SCHEMBL359650 0.85 ALDH1A1 (0.65) EPHX1ALDH1A1GAACYP3A4CYP2C9
SCHEMBL1424064 0.85 EPHX1 (0.84) EPHX1ALDH1A1GAATSHRMEN1
SCHEMBL8393719 0.85 EPHX1 (0.84) EPHX1ALDH1A1GAATSHRMEN1
Bicarbonate SCHEMBL6203780 0.84 EPHX1 (0.82) EPHX1ALDH1A1GAATSHRMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025097104-A1 THIENYL COMPOUNDS FOR THE TREATMENT OF A CENTRAL NERVOUS SYSTEM DISEASE OR DISORDER PGI DRUG DISCOVERY LLC (US) 2025-05-08 WO disclosed
WO-2013090929-A1 AMINO QUINOLINE DERIVATIVES INHIBITORS OF HCV GILEAD SCIENCES, INC. (US) 2013-06-20 WO disclosed