Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.61 |
| ▸ | BRS3 | P32247 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | GABRP | O00591 | 1/20 | 0.55 |
| ▸ | GABRD | O14764 | 1/20 | 0.55 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.55 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8999334 | 0.86 | SMN1; SMN2 (0.68) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL901463 | 0.85 | MAPT (0.69) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL30736497 | 0.85 | MAPT (0.69) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL7838780 | 0.85 | POLB (0.73) | KCNT1BRS3MAPTGAAHTT | |
| Hydrochloric Acid SCHEMBL9834221 | 0.84 | MAPT (0.67) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8998993 | 0.84 | KCNT1 (0.60) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL1388421 | 0.84 | KCNT1 (0.60) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8999421 | 0.81 | EGFR (0.64) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8999430 | 0.81 | MAPT (0.68) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8482904 | 0.79 | MAPT (0.75) | KCNT1BRS3MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087716-A2 | NEW ANTIBODY DRUG CONJUGATES (ADCS) AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-20 | — | — | WO | disclosed |