Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.60 |
| ▸ | BRS3 | P32247 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | CTSL | P07711 | 1/20 | 0.54 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1388421 | 0.93 | KCNT1 (0.60) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8998923 | 0.89 | KMT2A (0.64) | BRS3MAPTKDM4EMEN1TSHR | |
| SCHEMBL8999101 | 0.88 | KMT2A (0.56) | KCNT1BRS3MAPTKDM4EMEN1 | |
| SCHEMBL8999337 | 0.87 | GPR84 (0.54) | KCNT1MAPTGAAHTTKMT2A | |
| Hydrochloric Acid SCHEMBL9834221 | 0.85 | MAPT (0.67) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8998979 | 0.85 | KCNT1 (0.55) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8999334 | 0.85 | SMN1; SMN2 (0.68) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL8999058 | 0.84 | KMT2A (0.57) | KCNT1BRS3MAPTKDM4EMEN1 | |
| SCHEMBL7838780 | 0.84 | POLB (0.73) | KCNT1BRS3MAPTGAAHTT | |
| SCHEMBL30736497 | 0.84 | MAPT (0.69) | KCNT1BRS3MAPTGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5556874-A | ENZYME INHIBITORS AS ANTICARCINOGENIC AGENTS | WARNER LAMBERT COMPANY (US) | 1996-09-17 | — | — | US | disclosed |
| US-5464861-A | Anticarcinogenic agents | WARNER-LAMBERT (US) | 1995-11-07 | — | — | US | disclosed |