Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TACR1 | P25103 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | HPGD | P15428 | 6/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13828053 | 1.00 | GAA (0.54) | GAAALDH1A1L3MBTL1TACR1SMN1; SMN2 | |
| Hydrochloric Acid SCHEMBL8520493 | 0.89 | HPGD (0.56) | GAAALDH1A1L3MBTL1TACR1SMN1; SMN2 | |
| SCHEMBL12527472 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1L3MBTL1TACR1SMN1; SMN2 | |
| SCHEMBL12525246 | 0.81 | ALDH1A1 (0.56) | GAAALDH1A1L3MBTL1TACR1SMN1; SMN2 | |
| SCHEMBL16252383 | 0.80 | GAA (0.44) | GAAALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL823534 | 0.79 | ALDH1A1 (0.65) | GAAALDH1A1L3MBTL1SMN1; SMN2HPGD | |
| SCHEMBL2394839 | 0.78 | QPCT (0.51) | — | |
| SCHEMBL21115031 | 0.77 | ALDH1A1 (0.50) | GAAALDH1A1L3MBTL1TACR1SMN1; SMN2 | |
| SCHEMBL12506940 | 0.77 | CDC7 (0.62) | MAPK1 | |
| SCHEMBL12506946 | 0.77 | CDC7 (0.62) | MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013087716-A2 | NEW ANTIBODY DRUG CONJUGATES (ADCS) AND THE USE THEREOF | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2013-06-20 | — | — | WO | disclosed |