Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | CCR2 | P41597 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709381 | 0.98 | KDM4E (0.47) | KDM4ESIGMAR1LMNAALDH1A1KCNJ1 | |
| SCHEMBL20145851 | 0.91 | KDM4E (0.43) | KDM4ESIGMAR1LMNAALDH1A1KCNJ1 | |
| SCHEMBL15047602 | 0.86 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1KCNH2L3MBTL1SMN1; SMN2 | |
| SCHEMBL16186965 | 0.85 | KDM4E (0.43) | KDM4ESIGMAR1LMNAALDH1A1KCNJ1 | |
| SCHEMBL15709382 | 0.83 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1KCNH2KMT2A | |
| SCHEMBL25271966 | 0.82 | KCNJ1 (0.46) | KDM4ELMNAALDH1A1KCNJ1KCNH2 | |
| SCHEMBL3420319 | 0.82 | KCNJ1 (0.46) | KDM4ELMNAALDH1A1KCNJ1KCNH2 | |
| SCHEMBL31539506 | 0.82 | KCNJ1 (0.46) | KDM4ELMNAALDH1A1KCNJ1KCNH2 | |
| SCHEMBL6852082 | 0.82 | KCNJ1 (0.46) | KDM4ELMNAALDH1A1KCNJ1KCNH2 | |
| Hydrochloric Acid SCHEMBL30287913 | 0.81 | KCNJ1 (0.45) | KDM4ELMNAALDH1A1KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140314670-A1 | CLICKED SOMATOSTATIN CONJUGATED ANALOGS FOR BIOLOGICAL APPLICATIONS | UNIVERSITE DE CERGY PONTOISE (FR) | 2014-10-23 | — | — | US | disclosed |
| WO-2013088395-A1 | CLICKED SOMATOSTATIN CONJUGATED ANALOGS FOR BIOLOGICAL APPLICATIONS | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140314670-A1 | CLICKED SOMATOSTATIN CONJUGATED ANALOGS FOR BIOLOGICAL APPLICATIONS | SSTR4, SSTR3, SSTR2 | KDM4E 1752/4885SIGMAR1 352/4885LMNA 1146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.