Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.38 |
| ▸ | KCNJ1 | P48048 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15709381 | 0.93 | KDM4E (0.47) | KDM4ESIGMAR1ALDH1A1ADRA1DADRA1A | |
| SCHEMBL15047614 | 0.91 | KDM4E (0.48) | KDM4ESIGMAR1ALDH1A1ADRA1DADRA1A | |
| SCHEMBL20145720 | 0.83 | SIGMAR1 (0.39) | SIGMAR1ALDH1A1KCNH2KMT2A | |
| SCHEMBL20145870 | 0.79 | FOLH1 (0.34) | SIGMAR1ALDH1A1 | |
| SCHEMBL15709382 | 0.78 | SIGMAR1 (0.43) | SIGMAR1ALDH1A1KCNH2KMT2A | |
| SCHEMBL25271966 | 0.77 | KCNJ1 (0.46) | KDM4EALDH1A1KCNJ1KCNH2L3MBTL1 | |
| SCHEMBL3420319 | 0.77 | KCNJ1 (0.46) | KDM4EALDH1A1KCNJ1KCNH2L3MBTL1 | |
| SCHEMBL31539506 | 0.77 | KCNJ1 (0.46) | KDM4EALDH1A1KCNJ1KCNH2L3MBTL1 | |
| SCHEMBL6852082 | 0.77 | KCNJ1 (0.46) | KDM4EALDH1A1KCNJ1KCNH2L3MBTL1 | |
| SCHEMBL15047602 | 0.77 | SIGMAR1 (0.42) | SIGMAR1ALDH1A1KCNH2L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2922830-B1 | SYNTHESIS OF IMIDAZO(1,2-A)PYRAZIN-4-IUM SALTS FOR THE SYNTHESIS OF 1,4,7-TRIAZACYCLONONANE (TACN) AND N- AND/OR C-FUNCTIONALIZED DERIVATIVES THEREOF | UNIV BOURGOGNE (FR) | 2018-05-16 | — | — | EP | disclosed |