Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | UBE2M | P61081 | 1/20 | 0.32 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | SI | P14410 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2139183 | 0.76 | MEN1 (0.49) | NPC1RAB9AMAPTCYP1A2MAPK1 | |
| SCHEMBL20869346 | 0.71 | MEN1 (0.43) | NPC1MAPTCYP1A2MAPK1ALDH1A1 | |
| SCHEMBL21174548 | 0.71 | MEN1 (0.43) | NPC1MAPTCYP1A2MAPK1ALDH1A1 | |
| SCHEMBL30441109 | 0.71 | MEN1 (0.43) | NPC1MAPTCYP1A2MAPK1ALDH1A1 | |
| SCHEMBL16757501 | 0.67 | CYP1A2 (0.44) | NPC1CYP1A2MAPK1SLC6A2SLC6A4 | |
| SCHEMBL14458560 | 0.67 | HTR7 (0.47) | NPC1CYP1A2MAPK1SLC6A2SLC6A4 | |
| SCHEMBL25171316 | 0.66 | SLC6A2 (0.40) | NPC1MAPTCYP1A2MAPK1ALDH1A1 | |
| SCHEMBL20615090 | 0.66 | SLC6A2 (0.40) | NPC1CYP1A2MAPK1ALDH1A1SLC6A2 | |
| SCHEMBL14701534 | 0.65 | MEN1 (0.42) | NPC1MAPTCYP1A2MAPK1ALDH1A1 | |
| SCHEMBL2672974 | 0.65 | CYP1A2 (0.46) | NPC1CYP1A2MAPK1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8471035-B1 | Two-photon absorbing arylamine-endcapped and dialkylfluorene-bridged benzobisthiazole compounds with high oleophilicity | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) | 2013-06-25 | — | — | US | disclosed |