SCHEMBL14701534

SCHEMBL14701534

Brc1ccc2c(c1)C(c1ccccc1)c1cc(Br)ccc1-2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.42
KMT2A Q03164 3/20 0.42
NPC1 O15118 1/20 0.42
GAA P10253 1/20 0.42
PTPRC P08575 1/20 0.39
MAPK1 P28482 3/20 0.39
CYP1A2 P05177 2/20 0.39
LMNA P02545 1/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
MAPT P10636 1/20 0.39
HTR2B P41595 1/20 0.39
CYP19A1 P11511 1/20 0.38
KDM1A O60341 2/20 0.37
SLC6A2 P23975 1/20 0.37
SLC6A4 P31645 1/20 0.37
SLC6A3 Q01959 1/20 0.37
CHEK1 O14757 1/20 0.37
AURKA O14965 1/20 0.37
DAPK3 O43293 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21174548 0.94 MEN1 (0.43) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL30441109 0.94 MEN1 (0.43) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL20869346 0.94 MEN1 (0.43) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL12873511 0.85 KDM1A (0.42) MEN1KMT2ANPC1GAAMAPK1
SCHEMBL17209482 0.85 S100A4 (0.39) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL14185426 0.83 CYP1A2 (0.46) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL12156932 0.83 HAO1 (0.41) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL10042990 0.82 CYP1A2 (0.50) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL31448286 0.81 ADRA2A (0.35) MEN1KMT2ANPC1GAAPTPRC
SCHEMBL14212634 0.80 ALDH1A1 (0.44) MEN1KMT2ANPC1GAAMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3195378-B1 HOLE TRANSPORTING COMPOSITIONS CAMBRIDGE DISPLAY TECH LTD (GB) 2019-08-21 EP disclosed
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-07-20 US disclosed
WO-2013021180-A1 LIGHT EMITTING POLYMERS AND DEVICES CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2013-02-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170207393-A1 HOLE TRANSPORTING COMPOUNDS AND COMPOSITIONS SP1, NR0B1, C1S MEN1 358/4885KMT2A 1650/4885NPC1 16/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.