Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.51 |
| ▸ | CCR1 | P32246 | 3/20 | 0.51 |
| ▸ | CCR5 | P51681 | 3/20 | 0.51 |
| ▸ | CCR8 | P51685 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | ALPL | P05186 | 1/20 | 0.51 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.51 |
| ▸ | ALPI | P09923 | 1/20 | 0.51 |
| ▸ | ALPG | P10696 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | CBFB | Q13951 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15061960 | 0.88 | CCR1 (0.50) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL15024091 | 0.88 | KDM4E (0.67) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL15048694 | 0.86 | KDM4E (0.51) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL4367769 | 0.85 | KDM4E (0.62) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL31635769 | 0.85 | KDM4E (0.62) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL1991845 | 0.83 | KDM4E (0.64) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL1991759 | 0.81 | KDM4E (0.56) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL2768788 | 0.81 | KDM4E (0.56) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL923281 | 0.81 | KDM4E (0.56) | KDM4ECCR1CCR5CCR8LMNA | |
| SCHEMBL18679988 | 0.81 | KDM4E (0.56) | KDM4ECCR1CCR5CCR8LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607381-B1 | FUNCTIONALIZED ELASTOMER, RUBBER COMPOSITION AND TIRE | GOODYEAR TIRE & RUBBER (US) | 2018-01-24 | — | — | EP | disclosed |
| US-9416211-B2 | Rubber composition and pneumatic tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2016-08-16 | — | — | US | disclosed |
| EP-2735587-B1 | Self-healing rubber composition and tire or article of manufacture | GOODYEAR TIRE & RUBBER (US) | 2016-07-20 | — | — | EP | disclosed |
| US-20160083494-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | GOODYEAR TIRE & RUBBER COMPANY, THE | 2016-03-24 | — | — | US | disclosed |
| US-9243135-B2 | Rubber composition and runflat tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2016-01-26 | — | — | US | disclosed |
| US-9163101-B2 | Rubber composition and pneumatic tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2015-10-20 | — | — | US | disclosed |
| US-20150232649-A1 | RUBBER COMPOSITION AND RUNFLAT TIRE | THE GOODYEAR TIRE & RUBBER COMPANY | 2015-08-20 | — | — | US | disclosed |
| US-9050856-B2 | Rubber composition and runflat tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2015-06-09 | — | — | US | disclosed |
| CN-103172916-B | Functionalized elastomer, rubber composition and tire | GOODYEAR TIRE & RUBBER | 2015-05-27 | — | — | CN | disclosed |
| US-8962730-B2 | Self-healing rubber composition and tire | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2015-02-24 | — | — | US | disclosed |
| US-8859687-B2 | Functiontionalized elastomer | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-10-14 | — | — | US | disclosed |
| US-20140148555-A1 | SELF-HEALING RUBBER COMPOSITION AND TIRE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2014-05-29 | — | — | US | disclosed |
| EP-2735587-A2 | Self-healing rubber composition and tire or article of manufacture | The Goodyear Tire & Rubber Company (US) | 2014-05-28 | — | — | EP | disclosed |
| US-20130165596-A1 | FUNCTIONTIONALIZED ELASTOMER | GOODYEAR TIRE & RUBBER COMPANY, THE | 2013-06-27 | — | — | US | disclosed |
| US-20130160912-A1 | RUBBER COMPOSITION AND RUNFLAT TIRE | MRUK RALF (LU) | 2013-06-27 | — | — | US | disclosed |
| US-20130160911-A1 | RUBBER COMPOSITION AND PNEUMATIC TIRE | MRUK RALF (LU) | 2013-06-27 | — | — | US | disclosed |
| EP-2607381-A1 | Functionalized elastomer, rubber composition and tire | The Goodyear Tire & Rubber Company (US) | 2013-06-26 | — | — | EP | disclosed |