SCHEMBL1991759

SCHEMBL1991759

Cc1ccc(-c2ccnc(-c3cccc(-c4ccccn4)n3)c2)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.56
TP53 P04637 3/20 0.56
SMN1; SMN2 Q16637 3/20 0.56
CCR1 P32246 3/20 0.56
CCR5 P51681 3/20 0.56
CCR8 P51685 3/20 0.56
LMNA P02545 2/20 0.56
ALPL P05186 1/20 0.56
HSP90AA1 P07900 1/20 0.56
ALPI P09923 1/20 0.56
ALPG P10696 1/20 0.56
ALOX15 P16050 1/20 0.56
MAPK1 P28482 1/20 0.56
HTT P42858 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
TGFBR1 P36897 2/20 0.51
GRM5 P41594 3/20 0.49
PKM P14618 2/20 0.49
MEN1 O00255 2/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12339158 0.94 TGFBR1 (0.56) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL15024091 0.92 KDM4E (0.67) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL31635769 0.89 KDM4E (0.62) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL4367769 0.89 KDM4E (0.62) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL27085488 0.88 KDM4E (0.56) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL1991845 0.87 KDM4E (0.64) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL31517145 0.87 CCR1 (0.55) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL700298 0.87 CCR1 (0.55) KDM4ETP53SMN1; SMN2CCR1CCR5
SCHEMBL30074397 0.85 CCR1 (0.53) KDM4ETP53SMN1; SMN2CCR1CCR5
Hydrochloric Acid SCHEMBL9225985 0.85 CCR1 (0.53) KDM4ETP53SMN1; SMN2CCR1CCR5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2001849-B1 PYRIDINE AND PYRIMIDINE DERIVATIVES AS MGLUR2 ANTAGONISTS HOFFMANN LA ROCHE (CH) 2014-11-26 EP claimed
US-7618913-B2 Coordination catalyst containing an organosilicon compound , nitrogen compound, transition metal compound and magnesiumon compound on catalyst support FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-11-17 US claimed
US-20080058198-A1 Highly active alpha-olefin copolymerization catalyst system FORMOSA PLASTICS CORPORATION, U.S.A. 2008-03-06 US claimed
US-11952445-B2 Ethylene/alpha-olefin copolymers for better optical and mechanical properties and processability of film made therefrom FORMOSA PLASTICS CORPORATION, USA (US) 2024-04-09 US disclosed
US-20220153886-A1 Ethylene/Alpha-Olefin Copolymers for Better Optical and Mechanical Properties and Processability of Film Made Therefrom FORMOSA PLASTICS CORPORATION, USA 2022-05-19 US disclosed
US-10724903-B2 Polymer encapsulated particles as surface enhanced Raman scattering probes NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2020-07-28 US disclosed
US-20190352439-A1 Ethylene/Alpha-Olefin Copolymers for Better Optical and Mechanical Properties and Processability of Film Made Therefrom FORMOSA PLASTICS CORPORATION, USA 2019-11-21 US disclosed
US-10344105-B2 Process for making polyethylene copolymers with a reversed comonomer distribution FORMOSA PLASTICS CORPORATION, USA (US) 2019-07-09 US disclosed
US-20190040160-A1 Process for Making Polyethylene Copolymers with a Reversed Comonomer Distribution FORMOSA PLASTICS CORPORATION, USA 2019-02-07 US disclosed
EP-2828304-B1 ETHYLENE COPOLYMERS WITH A NOVEL COMPOSITION DISTRIBUTION AND PROCESSES FOR MAKING THE SAME FORMOSA PLASTICS CORP USA (US) 2018-03-21 EP disclosed
US-9487608-B2 Ethylene copolymers with a novel composition distribution and processes for making the same FORMOSA PLASTICS CORPORATION, USA (US) 2016-11-08 US disclosed
US-20110151586-A1 POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES Nanyang Technological Yniversity 2011-06-23 US disclosed
WO-2009142604-A1 POLYMER ENCAPSULATED PARTICLES AS SURFACE ENHANCED RAMAN SCATTERING PROBES NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2009-11-26 WO disclosed
US-7618913-B2 Coordination catalyst containing an organosilicon compound , nitrogen compound, transition metal compound and magnesiumon compound on catalyst support FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2009-11-17 US disclosed
WO-2008027479-A2 HIGHLY ACTIVE ALPHA-OLEFIN COPOLYMERIZATION CATALYST SYSTEM FORMOSA PLASTICS CORPORATION, U.S.A. (US) 2008-03-06 WO disclosed
US-20080058198-A1 Highly active alpha-olefin copolymerization catalyst system FORMOSA PLASTICS CORPORATION, U.S.A. 2008-03-06 US disclosed
EP-1703976-A2 USE OF METAL COMPLEX COMPOUNDS COMPRISING PYRIDINE, PYRIMIDINE OR S-TRIAZINE DERIVED LIGANDS AS CATALYSTS FOR OXIDATIONS WITH ORGANIC PEROXY ACIDS AND/OR PRECURSORS OF ORGANIC PEROXY ACIDS AND H2O2 Ciba Specialty Chemicals Holding Inc. (CH) 2006-09-27 EP disclosed
WO-2005068074-A2 USE OF METAL COMPLEX COMPOUNDS COMPRISING PYRIDINE PRYIMIDINE OR S-TRIAZNE DERIVED LIGANDS AS CATALYSTS FOR OXIDATIONS WITH ORGANIC PEROXY ACIDS AND/OR PRECURSORS OF ORGANIC PEROXY ACID AND H2O2 CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2005-07-28 WO disclosed
EP-1383857-A2 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS Ciba SC Holding AG (CH) 2004-01-28 EP disclosed
WO-2002088289-A2 USE OF METAL COMPLEX COMPOUNDS AS OXIDATION CATALYSTS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-11-07 WO disclosed