Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 4/20 | 0.46 |
| ▸ | EIF4E | P06730 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048832 | 1.00 | SMN1; SMN2 (0.46) | SMN1; SMN2TRPV1HTTEIF4EALDH1A1 | |
| SCHEMBL1785731 | 0.85 | MEN1 (0.53) | SMN1; SMN2TRPV1HTTALDH1A1KDM4E | |
| SCHEMBL28106801 | 0.80 | ALDH1A1 (0.47) | SMN1; SMN2TRPV1HTTALDH1A1KDM4E | |
| SCHEMBL14089956 | 0.79 | TRPV1 (0.58) | SMN1; SMN2TRPV1ALDH1A1TSHRKDM4E | |
| SCHEMBL16097359 | 0.79 | ERN1 (0.51) | TRPV1ALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL15048943 | 0.79 | KDM4E (0.47) | SMN1; SMN2TRPV1ALDH1A1KDM4ETDP1 | |
| SCHEMBL1736168 | 0.76 | MEN1 (0.57) | SMN1; SMN2TRPV1HTTALDH1A1KDM4E | |
| SCHEMBL4880921 | 0.76 | P2RX7 (0.60) | — | |
| SCHEMBL15049097 | 0.75 | KDM4E (0.44) | SMN1; SMN2EIF4EALDH1A1KDM4ETDP1 | |
| SCHEMBL444703 | 0.74 | ALDH1A1 (0.53) | TRPV1ALDH1A1TDP1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |