Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA3 | P07451 | 1/20 | 0.42 |
| ▸ | CA4 | P22748 | 1/20 | 0.42 |
| ▸ | CA6 | P23280 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | CA7 | P43166 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.42 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.42 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.42 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1786323 | 0.84 | GAA (0.51) | ALDH1A1IRAK4POLBGAAHPGD | |
| SCHEMBL11775476 | 0.81 | GAA (0.53) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL11948604 | 0.81 | ALDH1A1 (0.44) | ALDH1A1IRAK4CA12CA1CA2 | |
| SCHEMBL2617486 | 0.81 | ALDH1A1 (0.48) | ALDH1A1IRAK4POLBGAAHPGD | |
| SCHEMBL15048859 | 0.80 | MAPT (0.43) | ALDH1A1IRAK4CA12CA1CA2 | |
| SCHEMBL1785062 | 0.80 | GAA (0.52) | ALDH1A1CA12CA1CA2CA3 | |
| SCHEMBL14177481 | 0.79 | ALDH1A1 (0.45) | ALDH1A1IRAK4POLBEP300BCL2 | |
| SCHEMBL29152465 | 0.78 | KDM4E (0.49) | ALDH1A1IRAK4POLBGAAHPGD | |
| SCHEMBL15048783 | 0.77 | HSD17B10 (0.49) | ALDH1A1POLBGAAHPGDL3MBTL1 | |
| SCHEMBL10424032 | 0.77 | CSNK2A1 (0.49) | ALDH1A1IRAK4POLBGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |