Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | RORC | P51449 | 1/20 | 0.40 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA3 | P07451 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA6 | P23280 | 1/20 | 0.40 |
| ▸ | CA5A | P35218 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.40 |
| ▸ | CISD1 | Q9NZ45 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1788377 | 0.87 | GAA (0.46) | MAPTKDM4ETDP1ALDH1A1RORC | |
| Hydrochloric Acid SCHEMBL27796031 | 0.86 | GAA (0.44) | MAPTKDM4ETDP1ALDH1A1RORC | |
| Hydrochloric Acid SCHEMBL1787398 | 0.82 | LRRK2 (0.46) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL15048858 | 0.80 | ALDH1A1 (0.44) | MAPTNPC1RAB9APOLBALDH1A1 | |
| SCHEMBL1785840 | 0.79 | RAB9A (0.46) | MAPTNPC1RAB9AKDM4EPOLB | |
| Hydrochloric Acid SCHEMBL1787672 | 0.78 | RAB9A (0.46) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL11948604 | 0.77 | ALDH1A1 (0.44) | MAPTNPC1RAB9AALDH1A1RORC | |
| SCHEMBL1787070 | 0.76 | ALDH1A1 (0.55) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL15048881 | 0.74 | MAPT (0.50) | MAPTNPC1RAB9AKDM4EPOLB | |
| SCHEMBL2617486 | 0.74 | ALDH1A1 (0.48) | NPC1KDM4EPOLBALDH1A1RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607357-A1 | BENZOTHIAZOLES AS GHRELIN RECEPTOR MODULATORS | Astrazeneca AB (SE) | 2013-06-26 | — | — | EP | disclosed |