Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 4/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FKBP4 | Q02790 | 3/20 | 0.30 |
| ▸ | FKBP5 | Q13451 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048877 | 1.00 | FKBP1A (0.37) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL15049038 | 1.00 | FKBP1A (0.37) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL15049057 | 1.00 | FKBP1A (0.37) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL18940925 | 0.85 | FKBP1A (0.34) | FKBP1ACYP2C19 | |
| SCHEMBL15048934 | 0.81 | FKBP1A (0.39) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL15048902 | 0.81 | FKBP1A (0.39) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL15048935 | 0.81 | FKBP1A (0.39) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL15048903 | 0.81 | FKBP1A (0.39) | FKBP1ACYP2C19FKBP4FKBP5 | |
| SCHEMBL15049838 | 0.78 | GAA (0.42) | — | |
| SCHEMBL15049159 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794566-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013091900-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607352-A1 | Pipecolate-diketoamides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-26 | — | — | EP | disclosed |