SCHEMBL18940925

SCHEMBL18940925

CCC1CCCCC1(O)C(=O)O

nearest known ligand 0.34

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FKBP1A P62942 1/20 0.34
CYP2C19 P33261 2/20 0.33
ARG1 P05089 3/20 0.32
ARG2 P78540 2/20 0.32
ALDH1A1 P00352 1/20 0.30
OPRM1 P35372 1/20 0.30
OPRD1 P41143 1/20 0.30
OPRK1 P41145 1/20 0.30
CYP1A2 P05177 1/20 0.30
LMNA P02545 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15049057 0.85 FKBP1A (0.37) FKBP1ACYP2C19
SCHEMBL15048876 0.85 FKBP1A (0.37) FKBP1ACYP2C19
SCHEMBL15049038 0.85 FKBP1A (0.37) FKBP1ACYP2C19
SCHEMBL15048877 0.85 FKBP1A (0.37) FKBP1ACYP2C19
SCHEMBL28472473 0.78 CYP2C19 (0.41) CYP2C19ARG1ARG2ALDH1A1CYP1A2
SCHEMBL15048902 0.78 FKBP1A (0.39) FKBP1ACYP2C19
SCHEMBL15048935 0.78 FKBP1A (0.39) FKBP1ACYP2C19
SCHEMBL15048934 0.78 FKBP1A (0.39) FKBP1ACYP2C19
SCHEMBL15048903 0.78 FKBP1A (0.39) FKBP1ACYP2C19
SCHEMBL3799713 0.77 GAA (0.44) CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10005754-B2 Form of spirodiclofen, a process for its preparation and use the same ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (HK) 2018-06-26 US disclosed
CN-107922368-A New forms of spirodiclofen, process for their preparation and their use 龙灯农业化工国际有限公司 2018-04-17 CN disclosed
WO-2017101515-A1 NOVEL FORM OF SPIRODICLOFEN, PROCESS FOR PREPARATION AND USE THEREOF ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-22 WO disclosed
US-20170166546-A1 NOVEL FORM OF SPIRODICLOFEN, A PROCESS FOR ITS PREPARATION AND USE THE SAME ROTAM AGROCHEM INTERNATIONAL COMPANY LIMITED (CN) 2017-06-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170166546-A1 NOVEL FORM OF SPIRODICLOFEN, A PROCESS FOR ITS PREPARATION AND USE THE SAME CYP2F1, REN, CYP4F11 FKBP1A 128/4885CYP2C19 11/4885ARG1 4468/4885
US-10005754-B2 Form of spirodiclofen, a process for its preparation and use the same CYP2F1, REN, VKORC1 FKBP1A 119/4885CYP2C19 9/4885ARG1 4558/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.