Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 2/20 | 0.34 |
| ▸ | FKBP4 | Q02790 | 1/20 | 0.33 |
| ▸ | FKBP5 | Q13451 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15048999 | 1.00 | FKBP1A (0.34) | FKBP1AFKBP4FKBP5MAPTCYP1A2 | |
| SCHEMBL15048929 | 1.00 | FKBP1A (0.34) | FKBP1AFKBP4FKBP5MAPTCYP1A2 | |
| SCHEMBL15049000 | 1.00 | FKBP1A (0.34) | FKBP1AFKBP4FKBP5MAPTCYP1A2 | |
| SCHEMBL2018073 | 0.83 | MAPT (0.33) | FKBP1AMAPTCYP1A2LMNATSHR | |
| SCHEMBL15048879 | 0.79 | MAPT (0.37) | FKBP1AFKBP4FKBP5MAPTCYP2C19 | |
| SCHEMBL15048842 | 0.79 | MAPT (0.37) | FKBP1AFKBP4FKBP5MAPTCYP2C19 | |
| SCHEMBL15048878 | 0.79 | MAPT (0.37) | FKBP1AFKBP4FKBP5MAPTCYP2C19 | |
| SCHEMBL15048843 | 0.79 | MAPT (0.37) | FKBP1AFKBP4FKBP5MAPTCYP2C19 | |
| SCHEMBL7439240 | 0.77 | CYP1A2 (0.37) | CYP1A2LMNACYP2C19 | |
| SCHEMBL15049057 | 0.76 | FKBP1A (0.37) | FKBP1AFKBP4FKBP5CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794566-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013091900-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607352-A1 | Pipecolate-diketoamides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-26 | — | — | EP | disclosed |