Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.74 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.62 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.62 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.62 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.62 |
| ▸ | LMNA | P02545 | 3/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.56 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.56 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.55 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26393855 | 0.92 | HPGD (0.68) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL26393843 | 0.92 | HPGD (0.68) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL15061775 | 0.88 | HPGD (0.67) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL26393871 | 0.88 | HPGD (0.62) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL28808203 | 0.85 | HPGD (1.00) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL26296600 | 0.82 | ASAH1 (0.62) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL13073412 | 0.81 | HDAC3 (0.78) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL3435489 | 0.81 | TRPV1 (0.84) | HDAC1HDAC3HDAC2HDAC8HDAC6 | |
| SCHEMBL7201053 | 0.81 | L3MBTL1 (0.89) | HPGDHDAC1HDAC3HDAC2HDAC8 | |
| SCHEMBL7746417 | 0.80 | HPGD (0.65) | HPGDHDAC1HDAC3HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2607367-A1 | Glycerol phenyl butyrate derivatives | Lunamed AG (CH) | 2013-06-26 | — | — | EP | disclosed |
| EP-2607367-A1 | Glycerol phenyl butyrate derivatives | Lunamed AG (CH) | 2013-06-26 | — | — | EP | disclosed |