Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.84 |
| ▸ | GAA | P10253 | 1/20 | 0.82 |
| ▸ | LMNA | P02545 | 1/20 | 0.82 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.75 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.75 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.75 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.75 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.75 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.75 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.75 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.75 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.75 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.75 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.75 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.75 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080237 | 0.95 | MEN1 (0.83) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL7763386 | 0.93 | MEN1 (0.86) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL26393850 | 0.92 | TRPV1 (1.00) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL8699067 | 0.92 | TRPV1 (0.78) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL9787349 | 0.91 | HDAC1 (0.77) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL2942358 | 0.90 | MEN1 (0.96) | TRPV1GAALMNAMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL6966911 | 0.89 | TRPV1 (0.74) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL1661081 | 0.89 | TRPV1 (0.76) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL8697144 | 0.87 | TRPV1 (0.71) | TRPV1GAALMNAMEN1KMT2A | |
| SCHEMBL31329317 | 0.87 | ALDH1A1 (1.00) | TRPV1GAALMNAKMT2AHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9284270-B2 | Boronic acid catalysts and methods of use thereof for activation and transformation of carboxylic acids | THE GOVERNERS OF THE UNIVERSITY OF ALBERTA (CA) | 2016-03-15 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | GREENCENTRE CANADA (CA) | 2014-05-22 | — | — | US | disclosed |
| EP-2684468-A1 | SALTY TASTE ENHANCER | Ajinomoto Co., Inc. (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-20140004243-A1 | SALTY TASTE ENHANCER | AJINOMOTO CO., INC. (JP) | 2014-01-02 | — | — | US | disclosed |
| EP-2675816-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | The Governors of the University of Alberta (CA) | 2013-12-25 | — | — | EP | disclosed |
| WO-2012109749-A1 | BORONIC ACID CATALYSTS AND METHODS OF USE THEREOF FOR ACTIVATION AND TRANSFORMATION OF CARBOXYLIC ACIDS | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2012-08-23 | — | — | WO | disclosed |
| EP-1846347-B1 | METHOD FOR THE USE OF [11C] CARBON MONOXIDE IN LABELING SYNTHESIS OF 11C-LABELLED COMPOUNDS BY THERMALLY INDUCED FREE RADICAL CARBONYLATION | GE HEALTHCARE LTD (GB) | 2012-05-30 | — | — | EP | disclosed |
| EP-1867630-B1 | PROCESS FOR PRODUCING TRICARBOXYLIC ACID TRIS(ALKYL-SUBSTITUTED CYCLOHEXYLAMIDE) | NEW JAPAN CHEM CO LTD (JP) | 2010-10-20 | — | — | EP | disclosed |
| WO-2004113351-A2 | BIFUNCTIONAL AMINO-BORON LEWIS ACID - LEWIS BASE CATALYST | UNIVERSITY OF DURHAM (GB) | 2004-12-29 | — | — | WO | disclosed |
| US-6117893-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 2000-09-12 | — | — | US | disclosed |
| US-5977365-A | HYPOGLYCEMIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1999-11-02 | — | — | US | disclosed |
| US-5962470-A | Heterocyclic compounds having anti-diabetic activity and their use | SANKYO COMPANY, LIMITED (JP) | 1999-10-05 | — | — | US | disclosed |
| US-5886014-A | TREATMENT AND/OR PROPHYLAXIS OF A VARIETY OF DISORDERS, INCLUDING HYPERLIPEMIA, HYPERGLYCEMIA, OBESITY, IMPAIRED GLUCOSE TOLERANCE (IGT), INSULIN RESISTANCE AND DIABETIC COMPLICATIONS | SANKYO COMPANY, LIMITED (JP) | 1999-03-23 | — | — | US | disclosed |
| US-5834501-A | TREATING DIABETES OR HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 1998-11-10 | — | — | US | disclosed |
| US-5739345-A | HYPOGLYCEMIC AND ANTIDIABETIC AGENTS | SANKYO COMPANY, LIMITED (JP) | 1998-04-14 | — | — | US | disclosed |
| US-5624935-A | ANTIDIABETIC AGENTS, HYPOGLYCEMIC AGENTS OR ANTILIPEMIC AGENTS | SANKYO COMPANY, LIMITED | 1997-04-29 | — | — | US | disclosed |
| EP-0676398-A2 | Heterocyclic compounds having anti-diabetic activity, their preparation and their use | SANKYO COMPANY LIMITED (JP) | 1995-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140142322-A1 | Boronic Acid Catalysts and Methods of Use Thereof for Activation and Transformation of Carboxylic Acids | BCAT1, ME1, BCAT2 | TRPV1 4862/4885GAA 184/4885LMNA 3215/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.