Known targets — ChEMBL curated mechanism
rplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Stearic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSB | P07858 | 1/20 | 0.40 |
| ▸ | CTSK | P43235 | 1/20 | 0.40 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14698302 | 0.93 | CTSK (0.44) | TDP1LMNACTSLCTSBCTSK | |
| SCHEMBL62157 | 0.93 | CTSK (0.44) | TDP1LMNACTSLCTSBCTSK | |
| Glycine SCHEMBL4305400 | 0.90 | CTSK (0.40) | TDP1LMNACTSLCTSBCTSK | |
| SCHEMBL19717782 | 0.90 | CTSK (0.42) | TDP1LMNACTSLCTSBCTSK | |
| Cinnamic Acid SCHEMBL14166230 | 0.87 | EGFR (0.44) | LMNACTSLCTSBCTSKALDH1A1 | |
| SCHEMBL3008176 | 0.85 | TDP1 (0.36) | TDP1LMNACTSLCTSBCTSK | |
| SCHEMBL670603 | 0.83 | LMNA (0.43) | TDP1LMNACTSLCTSBCTSK | |
| SCHEMBL30497044 | 0.83 | TDP1 (0.38) | TDP1LMNACTSLCTSBCTSK | |
| SCHEMBL30452264 | 0.83 | TDP1 (0.38) | TDP1LMNACTSLCTSBCTSK | |
| SCHEMBL29402668 | 0.83 | LMNA (0.39) | TDP1LMNACTSLCTSBCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2606725-A1 | Phenol derivatives as antimicrobial agents | Symrise AG (DE) | 2013-06-26 | — | — | EP | disclosed |