Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.55 |
| ▸ | FKBP1A | P62942 | 5/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.50 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | APP | P05067 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15049047 | 1.00 | KDM4E (0.55) | KDM4EFKBP1AMEN1KMT2AEPHX1 | |
| SCHEMBL21241611 | 0.87 | FKBP1A (0.49) | KDM4EFKBP1AMEN1KMT2A | |
| SCHEMBL22861528 | 0.87 | FKBP1A (0.49) | KDM4EFKBP1AMEN1KMT2A | |
| SCHEMBL14920847 | 0.85 | FKBP1A (0.52) | KDM4EFKBP1AMEN1KMT2AEPHX1 | |
| SCHEMBL15048986 | 0.85 | FKBP1A (0.52) | KDM4EFKBP1AMEN1KMT2AEPHX1 | |
| SCHEMBL10350287 | 0.82 | KDM4E (0.61) | KDM4EMEN1KMT2AEPHX1HTT | |
| SCHEMBL22861533 | 0.81 | FKBP1A (0.53) | KDM4EFKBP1A | |
| SCHEMBL21241612 | 0.81 | FKBP1A (0.53) | KDM4EFKBP1A | |
| SCHEMBL21540592 | 0.78 | KDM4E (0.76) | KDM4EMEN1KMT2AEPHX1HTT | |
| SCHEMBL22861532 | 0.77 | L3MBTL1 (0.47) | KDM4EMEN1KMT2ACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2794566-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2014-10-29 | — | — | EP | disclosed |
| WO-2013091900-A1 | PIPECOLATE-DIKETOAMIDES FOR TREATMENT OF PSYCHIATRIC DISORDERS | MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-27 | — | — | WO | disclosed |
| EP-2607352-A1 | Pipecolate-diketoamides for treatment of psychiatric disorders | Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) | 2013-06-26 | — | — | EP | disclosed |