Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.30 |
| ▸ | RARA | P10276 | 1/20 | 0.30 |
| ▸ | RARB | P10826 | 1/20 | 0.30 |
| ▸ | RARG | P13631 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14666697 | 0.77 | KDM4E (0.32) | NOTUMRARARARBRARG | |
| SCHEMBL3030847 | 0.76 | CYP17A1 (0.42) | — | |
| SCHEMBL14666749 | 0.73 | MAOB (0.40) | MAOBLMNA | |
| SCHEMBL15049784 | 0.70 | MAOB (0.34) | MAOBLMNA | |
| SCHEMBL15049903 | 0.70 | PTGES (0.33) | MAOB | |
| SCHEMBL12082364 | 0.69 | CHRM1 (0.38) | MAOBLMNARARARARBRARG | |
| SCHEMBL15049778 | 0.67 | CNR1 (0.30) | — | |
| SCHEMBL15049801 | 0.67 | RARA (0.31) | RARARARBRARG | |
| SCHEMBL14822879 | 0.67 | RARA (0.40) | RARARARBRARG | |
| SCHEMBL15049759 | 0.67 | MEN1 (0.32) | MAOBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2179994-B1 | FUSED BICYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORP (JP) | 2013-06-26 | — | — | EP | claimed |