SCHEMBL15049944

SCHEMBL15049944

Cc1ccccc1-c1cnc2ccc(C(=O)N3CCN(C(=O)C4CCCCC4)CC3)cn12

nearest known ligand 0.60

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
F2RL1 P55085 1/20 0.60
FASN P49327 1/20 0.49
TSHR P16473 2/20 0.48
KMT2A Q03164 3/20 0.47
MKNK1 Q9BUB5 6/20 0.46
MKNK2 Q9HBH9 6/20 0.46
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
NPSR1 Q6W5P4 1/20 0.44
IRAK4 Q9NWZ3 1/20 0.43
ADORA2A P29274 1/20 0.43
RIPK2 O43353 1/20 0.42
PLA2G7 Q13093 1/20 0.42
SLC6A7 Q99884 1/20 0.42
ACACB O00763 1/20 0.42
ACACA Q13085 1/20 0.42
EIF4E P06730 2/20 0.42
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15071125 0.89 PLA2G7 (0.54) F2RL1TSHRMKNK1MKNK2NPSR1
SCHEMBL15071122 0.86 F2RL1 (0.67) F2RL1FASNTSHRKMT2AMKNK1
SCHEMBL31503 0.76 ADORA2A (0.53) TSHRKMT2AMKNK1MKNK2MEN1
SCHEMBL31519 0.75 F2RL1 (1.00) F2RL1FASNTSHRKMT2AMEN1
SCHEMBL31554 0.71 MKNK1 (0.63) MKNK1MKNK2ADORA2AEIF4E
SCHEMBL15071118 0.71 MKNK1 (0.53) MKNK1MKNK2ADORA2AEIF4E
SCHEMBL31533 0.70 F2RL1 (0.82) F2RL1FASNKMT2AACACBACACA
SCHEMBL15071119 0.70 MKNK1 (0.52) KMT2AMKNK1MKNK2ADORA2A
SCHEMBL15071123 0.70 HPGD (0.56) MKNK1MKNK2ADORA2A
SCHEMBL31526 0.69 F2RL1 (0.90) F2RL1FASNTSHRKMT2AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2617721-A2 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME Neopharm Co., Ltd. (KR) 2013-07-24 EP disclosed
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME NEOPHARM CO.,LTD. (KR) 2013-06-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130165652-A1 NOVEL HETEROCYCLIC COMPOUND, AND COMPOSITION FOR TREATING INFLAMMATORY DISEASES USING SAME F2RL1, F2R, FPR2 F2RL1 1/4885FASN 2594/4885TSHR 4593/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.