Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 13/20 | 0.67 |
| ▸ | ABHD6 | Q9BV23 | 8/20 | 0.67 |
| ▸ | PLA2G7 | Q13093 | 6/20 | 0.67 |
| ▸ | FAAH | O00519 | 1/20 | 0.59 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14834372 | 0.82 | MGLL (0.76) | MGLLABHD6PLA2G7FAAH | |
| SCHEMBL28001461 | 0.81 | MGLL (0.57) | MGLLABHD6PLA2G7FAAH | |
| SCHEMBL15094223 | 0.80 | MGLL (1.00) | MGLLABHD6PLA2G7 | |
| SCHEMBL14834300 | 0.80 | MGLL (0.62) | MGLLABHD6PLA2G7 | |
| SCHEMBL14834481 | 0.80 | MGLL (0.68) | MGLLABHD6PLA2G7 | |
| SCHEMBL14834454 | 0.79 | MGLL (0.59) | MGLLABHD6PLA2G7 | |
| SCHEMBL20015397 | 0.79 | FAAH (0.66) | FAAHMAOB | |
| SCHEMBL14834018 | 0.78 | MGLL (0.59) | MGLLABHD6PLA2G7 | |
| SCHEMBL14834237 | 0.78 | MGLL (1.00) | MGLLABHD6PLA2G7 | |
| SCHEMBL14834289 | 0.78 | MGLL (0.66) | MGLLABHD6PLA2G7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103068797-B | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2015-03-11 | — | — | CN | claimed |
| EP-2576507-B1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI SA (FR) | 2017-04-05 | — | — | EP | disclosed |
| CN-103068797-B | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI SA | 2015-03-11 | — | — | CN | disclosed |
| US-8835418-B2 | Hexafluoroisopropyl carbamate derivatives, their preparation and their therapeutic application | SANOFI (FR) | 2014-09-16 | — | — | US | disclosed |
| US-20130165422-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | SANOFI (FR) | 2013-06-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130165422-A1 | HEXAFLUOROISOPROPYL CARBAMATE DERIVATIVES, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION | F7, MGMT, CA13 | MGLL 3200/4885ABHD6 1949/4885PLA2G7 1860/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.