Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 19/20 | 0.56 |
| ▸ | EGFR | P00533 | 14/20 | 0.56 |
| ▸ | CLK1 | P49759 | 1/20 | 0.52 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3945407 | 0.93 | KDR (0.54) | KDREGFR | |
| SCHEMBL1504837 | 0.91 | NTRK1 (0.53) | KDREGFRABCG2 | |
| SCHEMBL1504863 | 0.89 | KDR (0.58) | KDREGFR | |
| 4Sc-203 SCHEMBL29370845 | 0.88 | EGFR (0.64) | KDREGFR | |
| 4Sc-203 SCHEMBL1505017 | 0.88 | EGFR (0.64) | KDREGFR | |
| SCHEMBL3951600 | 0.86 | KDR (0.49) | KDREGFR | |
| SCHEMBL3951047 | 0.85 | EGFR (0.49) | KDREGFR | |
| SCHEMBL3949246 | 0.83 | KDR (0.60) | KDREGFR | |
| SCHEMBL3948584 | 0.83 | KDR (0.58) | KDREGFR | |
| SCHEMBL3948811 | 0.83 | KDR (0.60) | KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033094-A1 | SCHEDULE OF ADMINISTRATION OF BENZAZOLE DERIVATIVES IN THE TREATMENT OF LEUKEMIAS | 4SC AG (DE) | 2011-03-24 | — | — | WO | claimed |