Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.58 |
| ▸ | EGFR | P00533 | 16/20 | 0.58 |
| ▸ | BRAF | P15056 | 1/20 | 0.58 |
| ▸ | FLT1 | P17948 | 1/20 | 0.55 |
| ▸ | FLT4 | P35916 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| 4Sc-203 SCHEMBL29370845 | 0.95 | EGFR (0.64) | KDREGFRFLT4 | |
| 4Sc-203 SCHEMBL1505017 | 0.95 | EGFR (0.64) | KDREGFRFLT4 | |
| SCHEMBL3948584 | 0.95 | KDR (0.58) | KDREGFRBRAFFLT1FLT4 | |
| SCHEMBL1504947 | 0.94 | KDR (0.62) | KDREGFRBRAFFLT1FLT4 | |
| SCHEMBL1504836 | 0.91 | KDR (0.71) | KDREGFRBRAF | |
| SCHEMBL3948294 | 0.90 | EGFR (0.65) | KDREGFRBRAFFLT4 | |
| SCHEMBL1504849 | 0.90 | EGFR (0.67) | KDREGFRFLT4 | |
| SCHEMBL1504794 | 0.89 | EGFR (0.71) | KDREGFRBRAFFLT4 | |
| SCHEMBL3946971 | 0.89 | EGFR (0.67) | KDREGFRBRAF | |
| SCHEMBL1505089 | 0.89 | KDR (0.56) | KDREGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011033094-A1 | SCHEDULE OF ADMINISTRATION OF BENZAZOLE DERIVATIVES IN THE TREATMENT OF LEUKEMIAS | 4SC AG (DE) | 2011-03-24 | — | — | WO | claimed |