Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 20/20 | 0.60 |
| ▸ | EGFR | P00533 | 19/20 | 0.60 |
| ▸ | AURKA | O14965 | 4/20 | 0.54 |
| ▸ | ERBB2 | P04626 | 4/20 | 0.54 |
| ▸ | FLT4 | P35916 | 4/20 | 0.54 |
| ▸ | TEK | Q02763 | 4/20 | 0.54 |
| ▸ | AURKB | Q96GD4 | 4/20 | 0.54 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.53 |
| ▸ | BRAF | P15056 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3948294 | 0.97 | EGFR (0.65) | KDREGFRAURKAERBB2FLT4 | |
| SCHEMBL3951156 | 0.94 | EGFR (0.62) | KDREGFRAURKAAURKBBRAF | |
| SCHEMBL3948584 | 0.92 | KDR (0.58) | KDREGFRFLT4BRAF | |
| 4Sc-203 SCHEMBL1505017 | 0.92 | EGFR (0.64) | KDREGFRAURKAERBB2FLT4 | |
| 4Sc-203 SCHEMBL29370845 | 0.92 | EGFR (0.64) | KDREGFRAURKAERBB2FLT4 | |
| SCHEMBL3954550 | 0.91 | EGFR (0.67) | KDREGFRAURKAERBB2FLT4 | |
| SCHEMBL3946971 | 0.90 | EGFR (0.67) | KDREGFRAURKAAURKBBRAF | |
| SCHEMBL3947867 | 0.90 | EGFR (0.66) | KDREGFRAURKAERBB2FLT4 | |
| SCHEMBL3947312 | 0.90 | KDR (0.69) | KDREGFRAURKAERBB2FLT4 | |
| SCHEMBL3944324 | 0.89 | KDR (0.61) | KDREGFRERBB2FLT4TEK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514460-B2 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2009-04-07 | — | — | US | disclosed |
| US-20060135782-A1 | Benzazole analogues and uses thereof | 4SC AG (DE) | 2006-06-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060135782-A1 | Benzazole analogues and uses thereof | DCK, SBK3, DAPK3 | KDR 1657/4885EGFR 437/4885AURKA 139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.