Sugi Predict

Sugi Predict / Compounds / SCHEMBL1505210

SCHEMBL1505210

SCHEMBL1505210

C1CCC(NC2CCCCC2)CC1.CC(C)(C)OC(=O)NCCOCCOCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ EPHX1 P07099 2/20 0.54
▸ GAA P10253 2/20 0.43
▸ GBA1 P04062 1/20 0.39
▸ BTK Q06187 1/20 0.39
▸ MEN1 O00255 1/20 0.38
▸ KMT2A Q03164 1/20 0.38
▸ TDP1 Q9NUW8 1/20 0.37
▸ CTSS P25774 1/20 0.37
▸ CTSK P43235 1/20 0.37
▸ IDO1 P14902 1/20 0.36
▸ HDAC4 P56524 1/20 0.35
▸ HDAC1 Q13547 1/20 0.35
▸ HDAC6 Q9UBN7 1/20 0.35
▸ SUCNR1 Q9BXA5 1/20 0.35
▸ TLR2 O60603 1/20 0.35
▸ TLR1 Q15399 1/20 0.35
▸ CA12 O43570 1/20 0.34
▸ CA1 P00915 1/20 0.34
▸ CA2 P00918 1/20 0.34
▸ CA9 Q16790 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18788521 1.00 EPHX1 (0.54) EPHX1GAAGBA1BTKMEN1
SCHEMBL31465488 0.97 EPHX1 (0.56) EPHX1GAAGBA1BTKMEN1
SCHEMBL1261192 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL21069640 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL25695638 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL23728812 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL13699512 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL21071644 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL3617073 0.85 MEN1 (0.49) EPHX1GAAGBA1MEN1KMT2A
SCHEMBL25194819 0.84 MEN1 (0.49) EPHX1GAAMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250333696-A1 DNA-CHIMERIC ANTIGEN RECEPTOR T CELLS FOR IMMUNOTHERAPY UNIV ARIZONA STATE (US) 2025-10-30 — — US disclosed
US-12338459-B2 DNA-chimeric antigen receptor T cells for immunotherapy ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2025-06-24 — — US disclosed
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof FLAGSHIP PIONEERING, INC. (US) 2025-04-17 — — US disclosed
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-10-19 — — US disclosed
US-20230167450-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-06-01 — — US disclosed
US-20230158156-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-05-25 — — US disclosed
WO-2023049816-A9 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-04-27 — — WO disclosed
CN-115916219-A Bifunctional molecules and methods of use thereof 旗舰创业股份有限公司 2023-04-04 — — CN disclosed
CN-115916262-A Bifunctional molecules and methods of use thereof 旗舰创业股份有限公司 2023-04-04 — — CN disclosed
WO-2023049816-A2 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF FLAGSHIP PIONEERING, INC. (US) 2023-03-30 — — WO disclosed
EP-4126063-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF Flagship Pioneering, Inc. (US) 2023-02-08 — — EP disclosed
EP-3170812-B1 IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME FUJIFILM CORP (JP) 2019-05-29 — — EP disclosed
US-9795566-B2 Imidazole compound and liposome containing same FUJIFILM CORPORATION (JP) 2017-10-24 — — US disclosed
EP-3170812-A1 IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME Fujifilm Corporation (JP) 2017-05-24 — — EP disclosed
US-20170119667-A1 IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME FUJIFILM CORPORATION (JP) 2017-05-04 — — US disclosed
EP-2488032-B1 PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF EINSTEIN COLL MED (US) 2016-11-02 — — EP disclosed
US-8952150-B2 Prostaglandin transporter inhibitors and uses thereof ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2015-02-10 — — US disclosed
US-20120238577-A1 PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2012-09-20 — — US disclosed
EP-2488032-A1 PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF Albert Einstein College Of Medecine Of Yeshiva University (US) 2012-08-22 — — EP disclosed
WO-2011037610-A1 PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) 2011-03-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120238577-A1 PROSTAGLANDIN TRANSPORTER INHIBITORS AND USES THEREOF PTGIS, SLC2A1, SLC2A3 EPHX1 831/4885GAA 730/4885GBA1 1280/4885
US-20230158156-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, SNRPE, DDX21 EPHX1 4357/4885GAA 2107/4885GBA1 2737/4885
US-20170119667-A1 IMIDAZOLE COMPOUND AND LIPOSOME CONTAINING SAME NPC1L1, LETM1, STOML2 EPHX1 2915/4885GAA 2807/4885GBA1 235/4885
US-20230332145-A1 BIFUNCTIONAL MOLECULES AND METHODS OF USING THEREOF EFTUD2, DDX21, SNRPE EPHX1 4246/4885GAA 2888/4885GBA1 3270/4885
US-20250122502-A1 Bifunctional Molecules and Methods of Using Thereof EFTUD2, DDX21, SNRPE EPHX1 4246/4885GAA 2888/4885GBA1 3270/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.