SCHEMBL15053200

SCHEMBL15053200

NC(=O)[C@@H](N)CCCC(N)C(=O)CCCC[C@@H]1SC[C@@H]2NC(=O)N[C@@H]21

nearest known ligand 0.62

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 6/20 0.62
▸ MEN1 O00255 1/20 0.61
▸ ABL1 P00519 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ PKM P14618 1/20 0.61
▸ IDE P14735 1/20 0.61
▸ MAPK1 P28482 1/20 0.61
▸ KMT2A Q03164 1/20 0.61
▸ RIN1 Q13671 1/20 0.61
▸ L3MBTL1 Q9Y468 1/20 0.61
▸ HLCS P50747 6/20 0.54
▸ CA12 O43570 7/20 0.48
▸ CA1 P00915 7/20 0.48
▸ CA2 P00918 7/20 0.48
▸ CA9 Q16790 7/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23066879 1.00 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
SCHEMBL912652 0.91 TDP1 (0.74) TDP1MEN1ABL1LMNAPKM
SCHEMBL15647842 0.90 TDP1 (0.77) TDP1MEN1ABL1LMNAPKM
SCHEMBL2536441 0.89 TDP1 (0.62) TDP1MEN1ABL1LMNAPKM
Hydrochloric Acid SCHEMBL3417755 0.88 TDP1 (0.61) TDP1MEN1ABL1LMNAPKM
SCHEMBL6040739 0.86 TDP1 (0.67) TDP1MEN1ABL1LMNAPKM
SCHEMBL20417372 0.85 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM
SCHEMBL12372458 0.85 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM
Biotin SCHEMBL28084581 0.85 TDP1 (0.69) TDP1MEN1ABL1LMNAPKM
SCHEMBL23745168 0.85 TDP1 (0.85) TDP1MEN1ABL1LMNAPKM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9981044-B2 Activation of adaptive immune processes for the treatment of cancers and infectious diseases SUSAVION BIOSCIENCES, INC. (US) 2018-05-29 — — US disclosed
US-20170290922-A1 ACTIVATION OF ADAPTIVE IMMUNE PROCESSES FOR THE TREATMENT OF CANCERS AND INFECTIOUS DISEASES SUSAVION BIOSCIENCES, INC. 2017-10-12 — — US disclosed
WO-2016033602-A1 ACTIVATION OF ADAPTIVE IMMUNE PROCESSES FOR THE TREATMENT OF CANCERS AND INFECTIOUS DISEASES SUSAVION BIOSCIENCES, INC. (US) 2016-03-03 — — WO disclosed
US-20150299252-A1 COMPOSITIONS AND METHODS FOR MODULATING INNATE AND ADAPTIVE IMMUNE SYSTEMS SUSAVION BIOSCIENCES, INC. (US) 2015-10-22 — — US disclosed
US-20150299255-A1 COMPOSITIONS AND METHODS FOR MODULATING INNATE AND ADAPTIVE IMMUNE SYSTEMS SUSAVION BIOSCIENCES, INC. 2015-10-22 — — US disclosed
WO-2013096829-A2 ACTIVATION OF CELLULAR ASSAULT PROCESSES IN THE TREATMENT OF GLIOBLASTOMA MULTIFORME ARIZONA BIOMEDICAL RESEARCH COMMISSION (US) 2013-06-27 — — WO disclosed
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