Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 17/20 | 0.53 |
| ▸ | BRD4 | O60885 | 3/20 | 0.53 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13545265 | 0.81 | BRD4 (0.56) | TRPV1BRD4CREBBP | |
| SCHEMBL7533313 | 0.77 | AHR (0.50) | TRPV1 | |
| SCHEMBL4123663 | 0.77 | BRD4 (0.54) | TRPV1BRD4CREBBP | |
| SCHEMBL29606190 | 0.74 | PIK3CA (0.50) | BRD4 | |
| SCHEMBL3599751 | 0.74 | BRD4 (0.59) | TRPV1BRD4CREBBP | |
| SCHEMBL31490089 | 0.74 | BRD4 (0.54) | TRPV1BRD4CREBBP | |
| SCHEMBL21932292 | 0.73 | BRD4 (0.56) | TRPV1BRD4CREBBP | |
| SCHEMBL13090753 | 0.72 | BRD4 (0.61) | TRPV1BRD4CREBBP | |
| SCHEMBL4123040 | 0.71 | BRD4 (0.76) | TRPV1BRD4CREBBP | |
| SCHEMBL27554931 | 0.71 | BRD4 (0.59) | TRPV1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013096226-A1 | TRPV1 ANTAGONISTS | ABBVIE INC. (US) | 2013-06-27 | — | — | WO | claimed |