Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 3/20 | 0.50 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.50 |
| ▸ | CMA1 | P23946 | 2/20 | 0.50 |
| ▸ | CRBN | Q96SW2 | 2/20 | 0.49 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.49 |
| ▸ | TLK2 | Q86UE8 | 1/20 | 0.46 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.44 |
| ▸ | FABP7 | O15540 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5728126 | 0.88 | SMYD3 (0.64) | AHRSMYD3TLK2 | |
| SCHEMBL3662896 | 0.84 | CRBN (0.52) | AHRSMYD3CMA1CRBNEIF2AK2 | |
| SCHEMBL10545036 | 0.82 | TDP2 (0.56) | — | |
| SCHEMBL10576398 | 0.80 | CMA1 (0.49) | AHRSMYD3CMA1CRBNEIF2AK2 | |
| SCHEMBL395950 | 0.80 | TRPV1 (0.59) | CRBNTRPV1 | |
| SCHEMBL396156 | 0.79 | DDX3X (0.59) | SMYD3CRBNTRPV1FABP7FABP5 | |
| SCHEMBL6744135 | 0.79 | SMYD3 (0.64) | SMYD3CRBNFABP7FABP5 | |
| SCHEMBL6543874 | 0.78 | FADS1 (0.50) | TRPV1FABP7FABP5 | |
| SCHEMBL9833039 | 0.77 | LMNA (0.57) | AHRSMYD3CRBNTLK2TRPV1 | |
| SCHEMBL15328229 | 0.77 | CASP3 (0.49) | AHRCMA1CRBNTRPV1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1212318-A1 | SUBSTITUTED INDOLINONES AS TYROSINE KINASE INHIBITORS | Boehringer Ingelheim Pharma KG (DE) | 2002-06-12 | — | — | EP | disclosed |
| WO-2001016130-A1 | SUBSTITUTED INDOLINONES AS TYROSINE KINASE INHIBITORS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2001-03-08 | — | — | WO | disclosed |