Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 5/20 | 0.56 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.45 |
| ▸ | TUBB | P07437 | 1/20 | 0.45 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.45 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.45 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.45 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.45 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.45 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.45 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.45 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.45 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.45 |
| ▸ | TUBA1C | Q9BQE3 | 1/20 | 0.45 |
| ▸ | TUBB6 | Q9BUF5 | 1/20 | 0.45 |
| ▸ | TUBB2B | Q9BVA1 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31490089 | 0.84 | BRD4 (0.54) | BRD4CREBBPALDH1A1HTTPOLB | |
| SCHEMBL4123663 | 0.84 | BRD4 (0.54) | BRD4CREBBPTRPV1 | |
| SCHEMBL27202871 | 0.82 | ALDH1A1 (0.46) | BRD4LMNAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL1359221 | 0.78 | CRBN (0.59) | LMNAALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL29374811 | 0.78 | CRBN (0.59) | LMNAALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL3954158 | 0.77 | ALOX15 (0.47) | BRD4LMNAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL31098479 | 0.77 | CASP3 (0.55) | BRD4LMNAALDH1A1ALOX15HSD17B10 | |
| SCHEMBL29754229 | 0.77 | CRBN (0.64) | LMNAALDH1A1ALOX15HSD17B10TUBB4A | |
| SCHEMBL2497788 | 0.77 | CRBN (0.64) | LMNAALDH1A1ALOX15HSD17B10TUBB4A | |
| SCHEMBL19504111 | 0.77 | CASP3 (0.55) | BRD4LMNAALDH1A1ALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115151304-B | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2025-02-11 | — | — | CN | disclosed |
| CN-111132972-B | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2024-07-12 | — | — | CN | disclosed |
| US-20230124361-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-04-20 | — | — | US | disclosed |
| US-20230124361-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2023-04-20 | — | — | US | disclosed |
| US-11571423-B2 | Small molecule modulators of human sting | CURADEV PHARMA LIMITED (GB) | 2023-02-07 | — | — | US | disclosed |
| US-11571423-B2 | Small molecule modulators of human sting | CURADEV PHARMA LIMITED (GB) | 2023-02-07 | — | — | US | disclosed |
| CN-115151304-A | Small molecule interferon gene stimulating factor (STING) antagonists | 库拉德夫制药私人有限公司 | 2022-10-04 | — | — | CN | disclosed |
| EP-3642198-B1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LTD (GB) | 2022-03-16 | — | — | EP | disclosed |
| EP-3642198-B1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LTD (GB) | 2022-03-16 | — | — | EP | disclosed |
| WO-2021161230-A1 | SMALL MOLECULE STING ANTAGONISTS | CURADEV PHARMA PVT. LTD. (IN) | 2021-08-19 | — | — | WO | disclosed |
| US-20200147083-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2020-05-14 | — | — | US | disclosed |
| US-20200147083-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | CURADEV PHARMA LIMITED (GB) | 2020-05-14 | — | — | US | disclosed |
| CN-111132972-A | Small molecule modulators of human STING | 克拉德夫制药有限公司 | 2020-05-08 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11571423-B2 | Small molecule modulators of human sting | STING1, IRF3, CGAS | BRD4 972/4885CREBBP 62/4885LMNA 4164/4885 |
| US-20230124361-A1 | SMALL MOLECULE STING ANTAGONISTS | STING1, CGAS, MAVS | BRD4 3179/4885CREBBP 765/4885LMNA 2127/4885 |
| US-20200147083-A1 | SMALL MOLECULE MODULATORS OF HUMAN STING | STING1, IRF3, CGAS | BRD4 972/4885CREBBP 62/4885LMNA 4164/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.